Brain Disorders and Therapeutics

Wang is Director of Neuroapoptosis Drug Discovery Laboratory, Department of Neurosurgery, Brigham and Women’s Hospital/Harvard Medical School. Dr. Wang received her PhD from Hebrew University of Jerusalem. She did her postdoctoral training at University of Michigan and Harvard Medical School. Dr. Wang has published about 70 peer-reviewed articles and has served as the Guest Editor, Handling Editor, and Editorial Board Member for a number of peer-reviewed journals, as well as the scientist reviewer for institutes or foundations including NIH, DOD, BSF, and others, and invited reviewer for 30 peer-reviewed journals.

Identification of candidate therapeutics for Amyotrophic Lateral Sclerosis, Huntington’s disease, and ischemic stroke; Fundamental mechanisms of neurological diseases.

Yingxu Wang is professor of cognitive informatics, brain science and denotational mathematics. He is President of International Institute of Cognitive Informatics and Cognitive Computing (ICIC). He is Fellows of BCS, ICIC, WIF, and Senior Members of IEEE and ACM. He has held visiting professor positions at Oxford University (’95), Stanford University (‘08|’16), UC Berkeley (‘08), and MIT (‘12). He is the initiator of fields of cognitive informatics, denotational mathematics, abstract intelligence (aI), neural circuit theory, formal brain models, cognitive robots and cognitive machine learning. He is a top 2.5% scholar worldwide and top 10 at UCalgary according to Research Gate’s statistics.

Neuroinformatics, neurology, neural signaling systems, spike frequency modulation, SFM, cognitive informatics, mathematical models, neural networks, cognitive system, cognitive robots, brain-machine interface

Yingxu Wang is professor of cognitive informatics, brain science and denotational mathematics. He is President of International Institute of Cognitive Informatics and Cognitive Computing (ICIC). He is Fellows of BCS, ICIC, WIF, and Senior Members of IEEE and ACM. He has held visiting professor positions at Oxford University (’95), Stanford University (‘08|’16), UC Berkeley (‘08), and MIT (‘12). He is the initiator of fields of cognitive informatics, denotational mathematics, abstract intelligence (aI), neural circuit theory, formal brain models, cognitive robots and cognitive machine learning. He is a top 2.5% scholar worldwide and top 10 at UCalgary according to Research Gate’s statistics

Neuroinformatics, neurology, neural signaling systems, spike frequency modulation, SFM, cognitive informatics, mathematical models, neural networks, cognitive system, cognitive robots, brain-machine interface

Founding Member (2007) and Prime Vice-President of the Romanian Society for Neurorehabilitation (RoSNeRa) - affiliated to WFNR. Founding Member and Prime Vice-President of the Romanian Spinal Cord Society (RoSCoS) - affiliated to ISCoS) and ESCIF. Member of the International Spinal Cord Society (ISCoS, since 2000), World Federation for Neurorehabiliation (WFNR, since 2008), Euroacademia Multidisciplinaria Neurotraumatologica (EMN, since European Federation of NeuroRehabilitation (since 2014), International Parkinson and Movement Disorder Society (since 2016), and in many Romanian Scientific Societies. Coordinator of the Romanian team in 5 international projects, participant in 4 national projects. He participated to the educational project "eleanSCI.org", launched by ISCoS in 2012.

Actively implied in national educational prophylactic interventions, aimed to prevent severe central nervous lesions (TBI and SCI ─ http://www.worldsciday.org/romania_avs.html “Prevention of SCI AV for General Public 00:15 secs”). Co-author of 2 patent certificates (appointed by the Romanian State Office for Inventions and Marks, OSIM), 9 books, and over 60 published papers. Fluently in English and French.

Yingxu Wang is professor of cognitive informatics, brain science and denotational mathematics. He is President of International Institute of Cognitive Informatics and Cognitive Computing (ICIC). He is Fellows of BCS, ICIC, WIF, and Senior Members of IEEE and ACM. He has held visiting professor positions at Oxford University (’95), Stanford University (‘08|’16), UC Berkeley (‘08), and MIT (‘12). He is the initiator of fields of cognitive informatics, denotational mathematics, abstract intelligence (aI), neural circuit theory, formal brain models, cognitive robots and cognitive machine learning. He is a top 2.5% scholar worldwide and top 10 at UCalgary according to Research Gate’s statistics

Neuroinformatics, neurology, neural signaling systems, spike frequency modulation, SFM, cognitive informatics, mathematical models, neural networks, cognitive system, cognitive robots, brain-machine interface

Biography DR. MANUEL VELASCO STUDIES: HIGH SCHOOL AND COLLEGE: Liceo Francisco de Miranda, Los Teques, Venezuela, 1962 UNIVERSITY: Universidad Central de Venezuela, Caracas, Venezuela, 1968 POSTGRADE STUDIES: Intern IN Medicina Interna (CLINICAL PHARMACOLOGY), Hahnemann Medical College and Hospital, Philadelphia, Pa., USA. Fellowship IN Medicina Interna (CARDIOVASCULAR CLINICAL PHARMACOLOGY), Emory University School of Medicine, Atlanta, Ga., USA Julio 1972 – Diciembre 1974. DOCTORATE IN MEDICAL SCIENCES: Universidad Nacional del Zulia, Maracaibo, Estado Zulia, Venezuela, 1979. POSITIONS: Jefe de Catedra de Farmacología, Escuela de Medicina Vargas, Caracas, Venezuela, 2001-2003 Jefe de Departamento de Ciencias Fisiologicas, Escuela de Medicina Vargas, Caracas, Venezuela, 2001-2003 Coordinador General, Facultad de Medicina, Universidad Central de Venezuela, Caracas, Venezuela, 2002-2004 Director, Unidad de Farmacología Clínica, Hospital Vargas, Caracas, Venezuela, desde 1976 Director, Unidad de Hipertensión, Hospital Vargas, Caracas, Venezuela, desde 1985. Director, Unidad de Farmacología Clinica Cardiovascular y Respiratoria, Escuela de Medicina Vargas, Caracas, Venezuela, desde 2002

RESEARCH INTERESTS: Methodology in Radioisotopes, Advance course of Biostathistics, Medical course in Radioisotopes, Advance course of clinical pharmacology.

Kenneth Blum is widely designated as Father of Psychiatric Genetics because of the of the DRD2 gene and its correlation with various psychiatric disorders including the “Reward Defi ciency Syndrome” (RDS) which term he has coined. He is also known as the “Father of Neuro- Nutrient Therapy “ for his discovery of successful nutrient therapy for RDS. He holds numerous domestic and foreign patents and is co-founder and Chairman & CSO of LifeGen Inc. He is a former Full Professor in the Department of Pharmacology, University of Texas Health Science Center, San Antonio, Texas; Volunteer Professor in the Department of Psychiatry & McKnight Brain Institute, University of Florida College of Medicine, Gainesville, Florida and Adjunct Full Professor of Psychiatry at the University of Vermont College of Medicine, Burlington, Vermont. He currently serves as Neuroscience advisor for Dominion Diagnostics., LLC North Kingstown, Rhode island, Malibu Beach Recovery Center, Malibu Beach California, and is the Scientifi c Director of PATH Foundation NY, New York. He is an honorary Faculty of IIOAB, India. He has been recently appointed Chief Scientifi c Offi cer(CSO) of G&G Holistic Addiction Treatment Centers in North Miami Beach Florida. To his credit he has over 400 publications in peer reviewed journals, 14 books and has received many awards including a Lifetime Achievement Award from the National Institute of Holistic Addiction Studies.

neuropsychopharmacology,genetics,genetics of alcoholism, neuropsychiatry,pharmacogenetics and Blum's research has been recognized through numerous awards.

January 2003 – July 2005. Currently forming part of a professional training period at the General Sleep Disorders Unit in service of the Clinical Neurophysiology of the Complejo Hospitalario de Toledo, in which I was in charge of evaluating patients with various sleep disorders particularly; apnoea, narcolepsy, restless legs syndrome, REM nightmares, night-terrors, sleep paralysis, nocturnal epilepsy (55 of these patients suffer from chronic insomnia and are part of my research project), hypersomnia (2 publications) with the evaluation of more than 500 patients a year and 150 night polysomnographies a year.( Technical handling, recording and analysis). The technical handling and analysis of Multimodal evoked potentials (somatosensory, visual electroretinogram and trunk audiometry). While working at the Clinical Neurophysiology Service at the Toledo Hospital Complex I undertook a three-month July 2005- JULY de 2015, 10 YEARS professional experience in the Neurophysiology Clinic in the Private Medical Centre Virgen de la Caridad, in Cartagena, Murcia, Spain which works in conjunction with the Social Security hospitals, (Santa Maria del Rosell Hospital, Naval Hospital in Cartagena, and los Arcos Hospital in Santiago de la Ribera). During the last seven years in this Centre my work related to: 9 EEG. electroencephalography /week 45 EMG. electromyography/ week 1-2 PEAT evoked potential / week 20 PSGN polysomnography /week. Professional experience: Experience in the analysis of- electroencephalography ( young children and adults) and also: -polysomnography (System Medelec Profile y Medelec Synergy- Oxford. Keypoint Medtronic System (EMG). -Electromyography - Practical experience with analysis system PUM and sensory and motor conduction and also in electromyography. Medelec Synergy and Keypoint .-Oxford.

Neurology, Seminars of Neurology, Research Techniques in Neurology, Neurobiology of sleep, Physiology of excitable membranes, Inter-functional relation between the nervous and immune system.

Dr. Pant received his M.A. and Ph.D. degrees in Physics from Agra University, Agra, India. His postdoctoral studies were conducted on the mechanisms of electron and ion transport in model membrane systems at the Department of Biophysics at Michigan State University. He joined the Laboratory of Neurobiology in the NIMH as a senior staff fellow in 1974 with Dr. Ichiji Tasaki where he studied the function of the axonal cytoskeleton in the squid giant axon. In 1979 he moved to the NIAAA extending his studies on the neuronal cytoskeleton and the effects of alcohol on its regulation. Dr. Pant moved to the NINDS, Laboratory of Neurochemistry in 1987 where he is presently chief of the section on Cytoskeleton Regulation. His laboratory is studying the mechanisms of topographic regulation of neuronal cytoskeleton proteins by post-translational modification, including the role of kinase cascades in normal brain and during neurodegeneration

The major focus of this laboratory has been to study the mechanisms of topographic regulation of neuronal cytoskeletal proteins regulation by phosphorylation and neurodegeneration. In a normal physiological state, cytoskeletal proteins are phosphorylated extensively in the axonal compartment of a mature neuron. Although all the substrates, kinases, phosphatases and their regulators are synthesized in neuronal cell bodies, little or no cytoskeletal protein phosphorylation has been detected in the cell body compartment. Under a variety of neuropathological conditions, however, such as ALS, Alzheimers Disease, or Picks disease, hyperphosphorylation of these molecules has been found in abnormal aggregates within cell bodies, usually correlated with massive neuronal cell death. The mechanisms underlying these profound compartmental shifts in neuronal phosphorylation are not well understood.The normal physiological processes within neurons are controlled by signal transduction mechanisms that regulate the balance between protein kinase and protein phosphatase activities. We have shown that the most abundant and extensively phosphorylated motifs in the c-terminal domains (lys-ser-pro-, or KSP) are primarily phosphorylated by proline directed kinases, cdk5 and MAP kinases. Moreover, we have demonstrated that this phosphorylation is due to activation of the signal transduction cascade. Recently, we have focussed on the other part of this regulation, the protein phosphatases. The other project is to study the expression, regulation and role of neuronal Cdk5 in nerve cell function.Cdk5 is a unique multifunctional kinase. Unlike other cyclin-dependent kinases, it is expressed predominantly in post-mitotic neurons, its activity modulated by association with nervous system-specific propeins. Since its identification and characterization in our laboratory, we have been intensively studying its mechanisms of regulation and its role in nerve cell function.

Dr Felix U. Uduma, MB.BCh, FWACS, FICS is a senior Lecturer in Department Of Radiology,in Faculty Of Clinical Sciences, College Of Health Sciences, University Of Uyo, Uyo, Nigeria. He is the Head of Department of Radiology in University of Uyo,Nigeria. He is a former Adjunct Lecturer in Madonna University, Elele, Nigeria and also a former Consultant Radiologist, Polyclinic Bonanjo, Douala, Cameroon. Dr. Uduma is a member of Medical Advisory Board in University of Uyo teaching hospital, Nigeria. He is also an associate Editor of many journals including West African Journal of Radiology. He has published not less than 30 articles.

Medicine, choroid plexus calcifications,epilepsy, cerebral hemiatrophy in childhood

Dr. Mohan received his Bachelor of Science (HONS) degree in Pharmacology from University of Hertfordshire, England, UK in 2002. During this time, Dr. Mohan was awarded a research scholarship to study and perform research in the USA. During his one-year research scholarship, Dr. Mohan worked on understanding genes responsible for antibiotic resistance in ocean samples collected from the South Pole.After graduating with his B.Sc., Dr. Mohan had a short stint in big pharma., with Pfizer Inc., focusing his research efforts on sexual health and urology discovery. After Pfizer, Dr. Mohan returned to the USA after being accepted onto a Ph.D. program in Biomedical Science in the Dept. of Pharmacology & Physiology, College of Medicine at Oklahoma State Univ. After publishing his work on opioid neuropharmacology and graduating with his Ph.D. in 2008 Dr. Mohan accepted a postdoctoral assistant position at the Univ. of Iowa. During his time in Iowa, Dr. Mohan concentrated on gaining valuable experience pertaining clinical pain, focusing on postoperative pain and discovery of novel targets to alleviate acute pain following surgery.Dr. Mohan served as the President for the North Central Florida Chapter of the Society for Neuroscience (SfN) from 2013 – 2014. Dr. Mohan is a member of the Society for Neuroscience, American Heart Association and the International Society for Neuroimmunology. Dr. Mohan has taught and mentored numerous undergraduate and graduate students during his research career. Dr. Mohan is currently a Advisory Board Member for the Sia Brain Awareness Foundation and a peer-reviewer for the J. of Pain Research and on the editorial board of the J. Pharmaceutical Sciences. Dr. Mohan is also a coalition member for Cabell County Substance Abuse Prevention Partnership (CCSAPP) here in Huntington, WV.

Dr. Mohan’s current research focus is on understanding the exposure of neurotoxic substances during development and how they affect neural plasticity and neurovascular of the brain.

Abbas Alnaji had his Board degree of Neurosurgery from University of Baghdad and the consultant from Iraqi ministry of health 2015. In 2016 he became the member of editorial board for the journal of Neurology and Experimental Neural Science, by GAVIN publishers. He is also an Associate editor for Global Journal of Intellectual & Developmental Disabilities (GJIDD).Recently he has befit the editorial board member for SciFed Orthopedics & Rheumatology Research journal and Ocular Biology journal.

He is interested in research work and has eleven papers published in the field of surgical pathology causation.Interested in the biological bases of medic-surgical pathologies in his field.

Giuseppe Scalabrino studied at the School of Medicine of the University of Milan and received his M.D. degree magna cum laude in 1968. He has held a number of academic positions in the Faculty of Medicine of the University of Milan. He was Associate Professor of General Pathology between 1971 and 1985; full Professor of General Pathology from 1986 till 2014. He has been invited speaker in various conferences, mainly dealing with the role of polyamines in oncology and subsequently with the cobalamin (vitamin B12) neurotrophism. Among his numerous honors, he received the International Award "Roentgen" from Italian Accademia dei Lincei in Rome for oncological research in 1983. He is author of more than 100 scientific papers and reviewer of numerous International Journals. Dr. Scalabrino's studies of cobalamin neurotrophism have been mentioned and reviewed in 12 american textbooks of neurology, biochemistry, hematology, and vitaminology

From many years, Dr. Scalabrino is usually reviewer for many international journals in the field of neurobiology, oncology, and molecular biology.

Queen Mokhuane is presently Acting Executive Director: Student Affairs and is also the Professor and Head in the department of Clinical Psychology at Medunsa Campus. She has an extensive experience in academia, students, teaching and student life including management. She has also received training in the auditing of institutions of higher learning. She holds a doctoral degree in Psychology (UNISA) and fellow ship in Public Health obtained from the University of Washington, Seattle, USA and an Internship in HIV/AIDS at the Seattle Community Mental Health. Queen has been extensively involved with international organizations such as the Kellogg’s Foundation and assisted in the development of academic and research projects for the training of health care personnel. She has been also involved in Mental Health Policy Initiative (Department of Health SA) Children’s Rights (Human Rights Division) – Geneva. To this effect, she was a member of Committee on the Rights of the Child 1999-2001. She is a member of various professional organizations and has referred scientific papers. She has produced a booklet for training for the National Prosecuting Agency with regard to the identification of child abuse and the different forms of child abuse including intervention strategies. Currently she is Chairperson of the Professional Board for Psychology and Chairperson Health Committee of the HPCSA.

Psychology,member of various professional organizations and has referred scientific papers.

Dr. Nagaraj Pushparaj is the Director & Chief Consultant at PMN Physiotherapy Speciaality Pranikha Sports Medicine Pain Relief Centre and he is currently working as a consultant Neuro Science & Sports Medicine Rehabilitation Neuro Developmental Therapist at Be Well Hospitals.

Physiotherapy, Neuro Science & Sports Medicine and Neuro Rehabilitation.

born on April 12, 1959 in Pilsum (East Friesland); 1979-1986 Medical studies at the Medical University of Hanover; 1988 Promotion (magna cum laude) with the theme "Investigations of electrophysiological, biochemical and psychometric parameters in hepatic encephalopathy "; 1990-1993 assistant physician at the psychiatric clinic, University of Göttingen; 1997 Specialist physician for psychiatry and neurology, since also lead the working group "Molecular Neurobiology" of the Psychiatric Clinic, University Goettingen. Since 1999 he has been the Clinical Director of the Psychiatric Clinic. 2001 Acquisition of the Additional description Psychotherapie / Facharzt für Psychiatrie und Psychotherapie. 2002 Habilitation, since then: Extraordinariat (C3 professorship) for psychiatry and psychotherapy; Deputy. Clinic Director & Ltd. Oberarzt, Head of the Polyclinic & Institute's Institute, FriedrichAlexander-University Erlangen-Nuremberg; Head of the Research Laboratory for Molecular Neurobiology, clinic with polyclinic for psychiatry and psychotherapy, Friedrich-AlexanderUniversität Erlangen-Nuremberg

Molecular Neurobiology,psychiatry and psychotherapy.

• 2017 to continue Lancet Commissioner for LMIC • 2014 to continue member of Teaching Course Committee, World Federation of Neurology (WFN). • 2014 – 2016 member of Scientific Committee of European Academy of Neurology (EAN). • 2013-2014 Rector of University of Medicine, Tirana • 2010 to continue Faculty in CONy Congresses • 2010-2013 Health National Contact Point, European Commission, CORDIS Fp7 programme • 2003 to continue: reviewer of European Journal of Neurology, Clinical Epidemiology, Neuropsychiatric Disease and Treatment, Journal of Epidemiology and Community Health, Journal of Pediatric Epilepsy, Patients and Reference, British Journal of Pharmaceutical Research, British Journal of Medicine and Medical Research, International Neuropsychiatric Disease Journal, BMJ Case Reports, etc. • February 2003 – 2011 – Trainer of European Academy of Epilepsy. • 2000 to continue: Member of editing board of OA Publishing London, WebMed Central Brain Editor, Confinia Cephalalgica, Parma, Emilia-Romagna, Italy; Contributer in Cochrane MS; Albanian Medical Journal, Albanian Journal of Medical and Health Sciences, University of Medicine, Tirana, • 1998-2007 - President of Albanian Society of Neurology (ASN). • 1997 to continue - Head of the University Service of Neurology (UHC Mother Teresa, Tirana). • 1981 to continue - Lecturer: Faculty of Medicine, Neurology Department. University of Tirana (University of Medicine since January 2013).

Neurology

Dr. Umeton is Research Associate at the Institute of Neuroscience, Newcastle University, investigating the neural computations underlying visual perception and stereopsis. Dr. Umeton received her PhD and postgraduate studies from University of Calabria, Italy, but has gain extensive research experience working for Newcastle University (UK), Calgary University (CA) and Universidad Complutence de Madrid (ES) .

Neural computations underlying visual perception and stereopsis