Lynne Hughes has worked in clinical research for more than 33 years and has lived and worked during this time period in both the US and in Europe. She has been with IQVIA for 21 years and is currently Vice President and Global Head, Medical Strategy, Neurology. She has provided consultancy advice in Alzheimer’s disease, multiple sclerosis, acute care including TBI and stroke, migraine, epilepsy and pain, and has been involved in a number of investment opportunities within IQVIA. She sits on a number of advisory boards, with particular interest in neurocognitive assessment and design of appropriate studies to assess AD & neurocognitive dysfunction. She is a member of a number of steering and / or executive committees for clients and has responsibility for several consultancy programs for investment opportunities within all areas of neurology. Her current role is in developing evidence-based strategies for the most efficient conduct of clinical trials / programs for our clients and leads the Medical Strategy team which provides therapeutic input and expertise for conducting trials in subjects across all neurological and pain indications. She has been involved, to varying extents, in the development of every neurology product on the market today. She has been involved in all of IQVIAs AD trials – and this is more than 82 trials, many of which were global, over the past 10 years. She is PMP certified and has been since 2000 and this certification is up to date.

Alzheimer’s disease, Parkinson’s disease, Neurocognitive dysfunction.

Sam Vaknin is the author of Malignant Self-love: Narcissism Revisited as well as many other books and ebooks about topics in psychology, relationships, philosophy, economics, international affairs, and award-winning short fiction. He is Visiting Professor of Psychology, Southern Federal University, Rostov-on-Don, Russia and Professor of Finance and Psychology in CIAPS (Centre for International Advanced and Professional Studies). He was the Editor-in-Chief of Global Politician and served as a columnist for Central Europe Review, PopMatters, eBookWeb , and Bellaonline, and as a United Press International (UPI) Senior Business Correspondent. He was the editor of mental health and Central East Europe categories in The Open Directory and Suite101. His YouTube channels garnered 20,000,000 views and 85,000 subscribers. Currently, Sam Vaknin is the editorial board member of the following journals: Global Journal of Addiction and Rehabilitation Medicine, Journal of Clinical Review & Case Reports, Journal of Psychology Research, Journal of Neurology, Psychiatry, and Brain Research, Journal of Clinical Depression, Journal of Asclepius Medical Case Reports, Journal of Psychology and Psychiatry Studies.

Personality Disorders

Ivan Milanov is Director & Professor at the University Neurological Hospital “St. Naum”, Department of Movement Disorders and Chief of Neurological clinic of Movement Disorders. He is the Consultant of the Ministry of Health. Member of the Governmental commission for the positive drug list of Bulgaria for 3 mandates.He is the President of theBulgarian Neurological Society, Bulgarian Movement Disorders and Multiple Sclerosis Society, Bulgarian Headache and Pain Society, Bulgarian Society of Clinical Electromyography, Vice President of the Bulgarian Association of Neuroprotection and Neurodegeneration.

Headache,Back pain, Movement Disorders, Parkinson’s disease, Multiple sclerosis, Sleep disorders and anxiety, Clinical electromyography, Botox treatment

Dr. Drini DOBI was born in January 27th, 1969, and graduated as PhD in University of Tirana, Albania in 1992, and has done the specialization course in Neurology from 1994-1998 in University Hospital Centre "Mother Teresa", Tirana Albania. After his specialization, he has done some other minispecialization course for neurorehabilitation in Instituto Carlo Besta, Milano, Italy, San Carlo , Milan, Italy and Don Carlo Gnocchi Milano, Italy and minispecialization course for neurosonology in UHC "Sestre Milosrdnice" Zagreb, Croatia. He has a lot of publications in some medical periodics and has participated in some of AAN Annual Meetings with his works, EFNS and EAN conferences, with his works too, and some other Neurological Conferences abroad. His Masters is in Rehabilitation in Parkinson Disease, in 2005 and PhD in Physical Rehabilitation after stroke in 2015. He is also the Member of EAN Scientific Pannel of Neurorehabilitation ,Scientific Pannel of neurotoxicology, and General Neurology

Neurorehabilitation and Stroke

Dr. E. Faizo. is a certified licensed Medical Doctor specialized in Neurosurgery and spine surgery practicing in Murnau Hospital south Germany. He presented in international seminars, media interviews and conferences in Health Care and education. Member of the Advisory boards in many German medical companies. Member of the German and European Neurosurgical Societies.

Spine surgery in research and pain therapy , Neuromodulation

Dr.Jera KRUJA is a Member of Scientific Committee at European Academy of Neurology and Professor of Neurology at Mother Theresa University Hospital Center. Since 2014 she is (European representative) at Teaching Course Committee, World Federation of Neurology. During 2013-2014 she is a Rector of University of Medicine, Tirana and Member of editing board of OA Publishing London, WebMed Central Brain Editor, Albanian Medical Journal, Bulletin of Medical Sciences, University of Medicine, Tirana. She worked at Health National Contact Point, European Commission, CORDIS Fp7 programme(2010-2013). From 2003, she is a reviewer of European Journal of Neurology, Clinical Epidemiology, Neuropsychiatric Disease and Treatment, Journal of Epidemiology and Community Health, Journal of Pediatric Epilepsy. She is a Trainer of European Academy of Epilepsy since February 2003. She is the President of Albanian Society of Neurology (ASN) during 1998-2007

Neurology, Neuroradiology, Epidemiology

He founded SGNP Ltd - Neuro Therapy Specialist Services and Stroke & Brain Injury Specialist Services UK in early 2013 after years of successful Neuro Physiotherapy practice both in the NHS and privately. As Neuro Physiotherapist and Rehabilitation Director of SGNP Ltd he is responsible for clients with complex needs and background due to neurological conditions particularly Brain Injury & Stroke. He designs and update rehabilitation programs with the aim of maximising the functional outcomes of clients to bring them as close as possible to their previous level of functioning.

Neurological Physiotherapy & Occupational Therapy, Rehabilitation

Bachelor and Master in Clinical and Health Psychology at Aveiro University (Portugal) and internship in Coimbra Hospital University Centre (e.g., Intervention in Sleep Disorders and Pain Disorders). Later, worked as a psychologist and neuropsychologist. Also performed a research project in Biofeedback/Neurofeedback by the Foundation for Science and Technology (FCT). Concomitantly, made several national and international communications in various Congress as Guest Speaker in the field of Neuroscience. Editor in Chief and Founder of the International Journal of Psychology and Neuroscience and Editor in several Scientific Journals and Author of various articles in peer review journals. At the moment, is a Ph.D. student in Neuroscience at the Faculty of Medicine, University of Salamanca – Neurosciences Institute of Castilla y León

Experimental Psychology, Neuropsychology and Biological Rhythms, particularly in: Assessment and Neuropsychological Rehabilitation, Drug Abuse and Addiction, Behavioural

Kim Baden-Kristensen is the CEO and Co-founder of Brain+, which specializes in digital therapeutics for brain rehabilitation and remediation, specifically for the recovery of impaired cognitive functions due to injury or disease. It’s award winning Brain+ apps are being clinically tested in Parkinson’s disease, Major depressive disorder and Traumatic brain injury patients, and is being used by Danish national team athletes to enhance cognitive performance. Brain+ is also working on pre-symptomatic detection of Alzheimer’s disease in collaboration with leading European universities, providers, and patient organizations.

Cognitive Disorders, Brain Disorders

Dr. Fakhir Salman Al- Ani is a Professor of Department in Physiology and Pathology. He has completed graduation in MBBS from Baghdad University and post-graduation in Physiology and Pathology from Baghdad University and Ph.D. Physiology and Pathology from Baghdad University. He has more than 20 publications.

Physiology and Pathology

He was born in Tuzla on May 28, 1963. He finished elementary and high school as well as the medical faculty in Tuzla. He started working as an assistant trainee at the Institute of Pathophysiology, Faculty of Medicine Tuzla, University of Tuzla, in April 1989. Since October 1990, she works as a specialist at the Clinic for Orthopedics and Traumatology, JZU UKC Tuzla. By establishing the Department of Medical Informatics at the Faculty of Medicine, Tuzla was engaged as an assistant until 1996. As a companion of the wounded, he was sent to Iran in 1992. Since 1996 he has been employed at New Medical Center and National Medical Center, Abu Dhabi, UAE. Specialization in diagnostic radiology ends in 2003. Necessary knowledge from interventional vascular and neovascular radiology was acquired in 2003 at Rikshospitalet Oslo, University of Oslo, Norway. He received the title of Master of Medical Science after defending the topic under the title "Doppler ultrasonography and digital subtraction arteriography in the diagnosis of carotid artery disease", 2005. In November 2008 he was appointed Director of the Clinic for Radiology, Nuclear Medicine and Radiotherapy, JZU UKC Tuzla. In the same year, he received the title of Doctor of Medical Science after defending his work on the "Validity of computerized tomographic angiography in the diagnosis of cerebral vascular disease". He was appointed responsible teacher at the Department of Radiology and Nuclear Medicine at the Faculty of Medicine in Tuzla in May 2009. Since February 2011 he has been the Head of the Department of Medical Imaging in Radiology at the Pan-European University Apeiron in Banja Luka. He is currently serving as the President of the Tuzla Canton Medical Chamber. In October 2013 he was elected Chief of the Clinic for Radiology and Nuclear Medicine, JZU UKC Tuzla. Since November 2013, he has also been awarded the Diploma Manager in Healthcare at the Pan-European University Apeiron in Banja Luka. The teacher is responsible for the subject "General principles of health care" at the College of Medicine of the University of Tuzla from the school year 2009/10. He is a member of the commission for the specialist exam in "Diagnostic Radiology" since 2009. Member of the commission for evaluation and defense of master and doctoral papers in the field of radiology, informatics and physics.

Endovascular treatment of giant basilar artery aneurysm is a complex procedure that requires the work of an experienced team and a range of materials and techniques available. Treatment of a giant aneurysm of the basilar artery in the body which includes the initial parts of both arteriae cerebelaris posterior was a special kind of technical challenges and use techniques Waffle cone. Technically it was not possible to implement the classic waffle cone technique, and made modifications to the horizontal stenting in the right artery cerebelaris posterior, and above it are set Koil, and the aneurysm successfully closed with rear patent cerebellar artery. Technical correctly written procedure with good outcome for the patient left the question of objective verification of results. Using Voronoi diagrams and indirect visualization of the 3D models of aneurysms with the analysis of the dynamics of flow (flow dynamics), an objective verification of results. Results of verification coincide with the real results to the patient. The new method of analysis of endovascular treatment has proven to be an effective model verification results

Marina V. Zueva, Professor of Pathophysiology, PhD, Dr. Biol. Sci., graduated from the Lomonosov Moscow State University (Department of Physiology of Higher Nervous Activity), received her Ph.D. and Dr. Biol. Sci. degrees from Moscow Helmholtz Research Institute of Eye Diseases. Currently, she is the Head of the Division of Clinical Physiology of Vision at the Moscow Helmholtz Research Institute of Eye Diseases. Zueva is a member of International Society of Clinical Electrophysiology of Vision (ISCEV), European Association on Vision and Eye Research (EVER), European Society of Retina Specialists (EURETINA), the Society for Research on Biological Rhythms (SRBR). She has published over ten peer-reviewed papers in English (over 80 in Russian) and presented over 60 topics at international conferences.

Recently, we proposed and theoretically substantiated the hypothesis, which offers new approaches to treating neurodegenerative diseases of the retina and brain (Zueva, 2015). For the first time, we suggested that the impact of visual environmental cues of complex spatiotemporal structure on a person throughout his life is necessary for normal development and aging of the brain and visual system. The theory sets the link between the complexity of neural connections, nonlinear dynamics of physiological processes in the brain and the nonlinear characteristics of sensory cues. The loss in the complexity of neural networks in the retina and the brain develops in such socially relevant neurodegenerative diseases as glaucoma, diabetic retinopathy, Alzheimer’s disease, Parkinson’s disease, etc. The necessity of maintaining and strengthening of mental abilities in extreme situations and normal aging is a separate social and medical problem. The idea is to improve the scheme of neural circuits and brain’s function in normal and neurodegenerative diseases by nonlinear visual and other sensory stimuli with complex temporal structure through the reactivation of the brain plasticity. We can expect that the development of innovative non-drug technologies of impact on brain plasticity and definition of ways to manage this process will contribute to a more efficient recovery of neuronal contacts, cognitive functions, and overall functionality in patients with neurodegenerative disorders and amblyopia. The creation of devices for nonlinear sensory stimulation and the detection of mechanisms of its impact on the brain are crucial for therapeutic strategies, which can underlay of future breakthrough technologies.

Dr Khaled Goher has more than 15 years of experience in academia in Egypt, Oman, NZ and the UK. He joined the Biomedical Engineering Program, Aston University in July 2017. Dr Goher is a customer and market-oriented academic with special dedication to research for the benefit of the society. His principal research interests lie in the field of mobile robotics, personal care and assistive robotics while considering needs, preferences and expectations of elderly. Dr Goher is currently investigating the possibility of developing robotic walking devices and other assistive devices for manipulation, fall prevention and elderly mobility. He published a book, many high-quality articles and book chapters and has presented several research papers in various peer-reviewed international conferences. He holds a BSc and MSc in Mechanical Engineering, a PhD in Control Engineering from the University of Sheffield, and a PGCertHE from Auckland University of Technology. He supervised number of PhD students, two Master students, many senior design projects and tens of course-based projects. Dr Goher is internationally-engaged with various non-profits organizations. He is a member in the management team of CLAWAR association and a member of number of standardisation committees of the British Standards Institution (BSI).

we shall update research interest soon.

Tarit Kanti Ghosh MSc, MBBS, born in 1968 is a renowned Neurologist in Bangladesh. Since the very childhood he was extraordinary talented i.e. he always stood as topper in the class. In secondary school certificate & higher secondary certificate public exam he was one of seven among about 400,000 students all over the country. Being a son of a doctor his ambition was to become a benevolent physician. Thereby, he completed his graduation from the then British recognized medical college in Dhaka, Bangladesh in 1993. Then he did post-graduation(MSc) in internal medicine & Neurology from United Kingdom. He accomplished “Leading edge neurology for the practising clinicians, 2014” course in University college of London, UK. Due to thirst of knowledge he is still studying in the university of Melbourne, Australia in the Specialist Certificate Course in Clinical Research Neuroscience.

Abstract : This article reflects how surgery irrespective to age and/or organ becomes a prospective major health problem. In general about 50-60% patients undergone surgery suffer mild/moderate/severe psycho-biological illness in future for a long time due to feeling or fear that he/she (1:3) has lost part of body inside unhealed or prolonged healing process. so some neuro-psychiatric symptoms such as anxiety,tension,emotion and depression gradually burden their life style eventually leading to chronic stress (about 10%) along with some major health risks in 4-6 yrs after surgery.

Weimin Yang has completed his PhD from Sichuan University and visitor scholor studies from Melbourne University. He is the professor in Dept. of Neurology, First Affiliated Hospital of Zhengzhou University, master tutor, innovative talents of Henan Province Health Sciences and Technology. His research work mainly related to clinical features of Chinese stroke patients, stroke register, dementia, and systematic reviews of therapies from China. He has published more than 25 papers in reputed journals.

Background: Intracerebral hemorrhage (ICH) is a significant contributor to global health-related morbidity and mortality. Due to improved recognition and treatment of atrial fibrillation by antithrombotics, there is an increase in proportion of ICH caused by warfarin and novel oral anticoagulants. However, the relationship between anticoagulation intensity and hematoma expansion remains unclear. We aimed to investigate the effects of INR on hematoma expansion post ICH. Methods: We conducted a retrospective study of all patients hospitalized for ICH at a single institution from January 1, 2008 and August 1, 2014. Hematoma volumes on initial CT scans and repeat CT scans were analyzed by the AxBxC/2 method. Univariate analysis was used to compare baseline characteristics and median regression analysis was performed to estimate the effects of INR and hematoma volume changes. Results: We included 224 consecutive ICH patients. Median age (IQR) was 68.5 years (17.0), 60.3% were male, median presentation Glasgow Coma Scale (GCS) (IQR) was 14.0 (4.0), median volume (IQR) of the first CT was 11.7ml (25.6), median INR (IQR) was 1.1 (0.2). We showed that INR and time lapsed between first CT and second CT were independent risk factors to hematoma volume change, adjusting for baseline hematoma volume and time. For each 1.0 increase in INR was associated with hematoma volume increased by 2.4ml (p = 0.015). Conclusions: We showed that high INR was associated with hematoma growth post ICH. However, the effects of reversal anticoagulation in the attenuation of hematoma growth remain uncertain and require confirmation in future randomized controlled studies.

Andreas Melzer was born in 1960 and after studies in Mainz and Tuebingen he qualified in Dentistry in 1989 and as MD in 1993. He has 20 years experiences in the development of medical technology for laparo-endoscopic surgery, interventional radiology, interventional & intraoperative MRI and image guided robotics, surgical instrumentation, surgical robotics and Nitinol devices with more than 60 patents and over 200 publications, more than 500 oral and poster presentations. He has served as co editor of three medical journals, Co-founder and partner of six start-up companies in the medical technology business and consultant for major vendors in medicine. He serves as organizer or chairman of various medical conferences and board member of six medical and technical societies. He currently is Professor of Medical Technology and Director of the Institute for Medical Science and Technology IMSaT, a joint venture of the Universities Dundee and St Andrews, Scotland.

Applied Biomedical Sciences, Dentistry

Sarah Crawford received a Master’s Degree in Biochemistry from Princeton University in 1982 and a PhD Degree from the Department of Biochemistry and Biophysics, Columbia University College of Physicians and Surgeons in 1987. She has been affiliated with Southern Connecticut State University for over 20 years and is currently the Full Professor in the Department of Biology where she teaches Genetics and Medical Genetics and directs a research laboratory in cancer biology. In 2013, she was awarded a patent by the US Patent Office for a novel cancer treatment for the brain cancer, glioblastoma.

Her research interest includes genetics and cancer biology.

Dr. Pant received his M.A. and Ph.D. degrees in Physics from Agra University, Agra, India. His postdoctoral studies were conducted on the mechanisms of electron and ion transport in model membrane systems at the Department of Biophysics at Michigan State University. He joined the Laboratory of Neurobiology in the NIMH as a senior staff fellow in 1974 with Dr. Ichiji Tasaki where he studied the function of the axonal cytoskeleton in the squid giant axon. In 1979 he moved to the NIAAA extending his studies on the neuronal cytoskeleton and the effects of alcohol on its regulation. Dr. Pant moved to the NINDS, Laboratory of Neurochemistry in 1987 where he is presently chief of the section on Cytoskeleton Regulation. His laboratory is studying the mechanisms of topographic regulation of neuronal cytoskeleton proteins by post-translational modification, including the role of kinase cascades in normal brain and during neurodegeneration.

The major focus of this laboratory has been to study the mechanisms of topographic regulation of neuronal cytoskeletal proteins regulation by phosphorylation and neurodegeneration. In a normal physiological state, cytoskeletal proteins are phosphorylated extensively in the axonal compartment of a mature neuron. Although all the substrates, kinases, phosphatases and their regulators are synthesized in neuronal cell bodies, little or no cytoskeletal protein phosphorylation has been detected in the cell body compartment. Under a variety of neuropathological conditions, however, such as ALS, Alzheimers Disease, or Picks disease, hyperphosphorylation of these molecules has been found in abnormal aggregates within cell bodies, usually correlated with massive neuronal cell death. The mechanisms underlying these profound compartmental shifts in neuronal phosphorylation are not well understood.The normal physiological processes within neurons are controlled by signal transduction mechanisms that regulate the balance between protein kinase and protein phosphatase activities. We have shown that the most abundant and extensively phosphorylated motifs in the c-terminal domains (lys-ser-pro-, or KSP) are primarily phosphorylated by proline directed kinases, cdk5 and MAP kinases. Moreover, we have demonstrated that this phosphorylation is due to activation of the signal transduction cascade. Recently, we have focussed on the other part of this regulation, the protein phosphatases. The other project is to study the expression, regulation and role of neuronal Cdk5 in nerve cell function.Cdk5 is a unique multifunctional kinase. Unlike other cyclin-dependent kinases, it is expressed predominantly in post-mitotic neurons, its activity modulated by association with nervous system-specific propeins. Since its identification and characterization in our laboratory, we have been intensively studying its mechanisms of regulation and its role in nerve cell function.

Awojoyogbe O. Bamidele has B.Sc (1986), M.Sc (1991) and obtained Ph.D (1997) from Federal University of Technology, Minna, Nigeria in collaboration with the Institute of Biomedical Engineering and Medical Informatics, University and ETH, Zurich, Switzerland. He won the 2003 Young African Mathematician Medal Award by African Mathematical Union at AMU-ICMS. He has published more than 50 papers in reputed journals and has served at various academic and administrative levels within the university.

computational magnetic resonance imaging and theranostic of brain tumors

Benjamin Chitambira completed his BSc Physiotherapy Honours degree from the University of Zimbabwe in 1995. He also completed a Postgraduate Certificate in Healthcare Leadership from the Open University in the UK in 2014. With over 19 years’ experience as a neuro-physiotherapist, he has been carrying out research on optokinetic chart stimulation as a clinical specialist physiotherapist in the Richard Stevens Stroke Unit for over 8 tears.With over 9 papers published in peer reviewed journals, he has been a peer reviewer for reputable journals and now serves as an editorial board member of peer reviewed journals.

Background: This presentation aims to describe optokinetic chart stimulation and its evolution as a recovery focused neurorehabilitation intervention. Stroke, traumatic brain injuries and critical care polyneuropathy and or myopathy can cause severe disability. Methods: The optokinetic chart is made of laminated A4 paper. It consists of repeated bundles of the colours of the rainbow. The chart is placed 20 centimetres in front of a patient’s face. It is moved from side to side atapproximately one cycle per second for 3 minutes. This is followed bymoving the chart up and down for 3 minutes and then forwards and backwards for another 3 minutes. Results: The first task was to identify which strokes benefited most from the intervention. A case seriespublished in 2011 identified that strokes not involving simultaneous infarcts or haemorrhages of parietal and temporal lobes recovered movements. A case control series published in 2014 demonstrated statistically significant upper limb recovery (P<0.05). The author has been pilot-testing to see if these differences are reproducible under randomized controlled trial conditions. First set of comparable results point to the potential of a future full trial achieving an all and none principle of the ideal scientific experiment. Preliminary efficacy has also been demonstrated in difficult to rehabilitate traumatic brain injuries and critical care polyneuropathies and or myopathies. Conclusion: Optokinetic chart stimulation shows promise as a novel recovery focused neurorehabilitation intervention. Further research with fully powered studies is required to provide evidence for its inclusion in future guidelines.

Dr. Badgaiyan received training in psychiatry and cognitive neuroscience at Harvard University, University of Pittsburgh and University of Oregon. His research is focused on the study of neural and neurochemical mechanisms that control the human brain functions. He developed the single scan dynamic molecular imaging technique to detect, map, and measure neurotransmitters released acutely in the human brain during task performance. Using this technique he studies dopaminergic control of human cognition and behavior. He is also interested in learning the nature of dysregulated dopamine neurotransmission in different psychiatric and neuropsychiatric conditions. He is particularly interested in the brain mechanisms that control conscious experiences at cortical and subcortical levels. His research is funded by NIMH, NINDS, VA, and various research foundations. Currently he is a Professor of Psychiatry and Neuromodulation scholar at University of Minnesota at Minneapolis. He is also the Director of Laboratory of Advanced Radiochemistry and the Laboratory of Molecular and Functional Imaging.

His research focuses on the study of brain mechanisms that are responsible for abnormal behavioral, cognitive and emotional processing. He uses a novel dynamic molecular imaging technique (that he recently developed), to detect changes in the brain neurochemistry. He also uses cutting edge functional MRI techniques to study psychiatric and neuropsychiatric conditions. He is primarily interested in understanding the behavioral and cognitive effects of dysregulated dopamine neurotransmission. His research is funded by the grants from National Institutes of Health and Veteran’s Administration.

Paria Arfa-Fatollahkhani is a medical intern of Iran University of Medical Sciences. Her enthusiasm to progress was intensified in the fields of neurology and neuroscience.

Short-term and long-term effects of treadmill training on the balance, functional capacity and quality of life in patients with Parkinson disease- A randomized clinical trial

Prof. Wang Rongfu has completed his Ph.D in Pharmacology from Toulouse Paul Sabatier University (Toulouse III), Toulouse, France in 1995. He received many awards and honors. Currently he is working as a Professor& Director, Department of Nuclear Medicine, Peking University Health Science Center & Peking University First Hospital.

....

Abbas Alnaji had his Board degree of Neurosurgery from University of Baghdad and the consultant from Iraqi ministry of health 2015. Interested in the biological bases of medic-surgical pathologies in his field. Took share as a speaker in more than 30 world events and conferences.

Illnesses treated symptomatically had got causes! categorizing them as of not known etiology is for a while! One of the main pillars to disclose these causes is the clinical trial treatment CTT; it may exceed the other means, where it works when they are depleted. CTT has its civilization to be applied. It is the link among philosophy, clinical practice and applied sciences. Starts by looking for the truth, maintained by the perseverance and end by the smart perception. A wise man once said ‘’ the admiration prevents from increment’’ this is the philosophy. It refers to the satisfaction in what if we are on, will stop further discovery of diseases causation. The route is paved with difficulties, so needs insistence. Results of CTT are the meticulous harvest of each step of the route. For that, in my career, by applying the above three basis, I can say, good gain was obtained through; chronic low back pain, carpal tunnel syndrome, MRI signs had been satisfactorily knew their reality. and several others will be discussed in more reality in near future, the ignition for that was the clinical trials.

Anatoly Uzdensky has completed his PhD at 1980 from Rostov State University (Russia). He is the principal investigator and Head of the Laboratory of Molecular Neurobiology in the Sothern Federal University (Rostov-on-Don, Russia). He has published more than 120 papers in reputed journals.

Neuroscience, Neuro-degeneration and Neuroprotection, Stroke, Cell-signaling and Proteomics.

Thomas F. Feiner is the director of the Institute for EEG-Neurofeedback since 2008 and teaches QEEG and Neurofeedback. He got his degree for Neurofeedback from Biofeedback Certification International Alliance in 2011.

Stroke, Traumatic Brain injury, Depression

1. Professor WK Tang was appointed to professor in the Department of Psychiatry, the Chinese University of Hong Kong in 2011. His main research areas are Addictions and Neuropsychiatry in Stroke. Professor Tang has published over 100 papers in renowned journals, and has also contributed to the peer review of 40 journals. He has secured over 20 major competitive research grants, including Health and Medical Research Fund, reference number: 02130726. Health and Medical Research Fund, reference number: 01120376. National Natural Science Foundation of China, reference number: 81371460. General Research Fund, reference number: 474513. General Research Fund, reference number: 473712. He has served the editorial boards of five scientific journals. He was also a recipient of the Young Researcher Award in 2007, awarded by the Chinese University of Hong Kong.

Stroke, Substance abuse, Postnatal depression

Prof. Trevor Archer has received his PhD in Uppsala University during the period of 1976-79. Currently, he is working as Professor in Gothenburg University. He has successfully completed his Administrative responsibilities as Head of Department and Dean of Faculty. His research has included biopsychology, health, sports, personality, learning and memory, neurotoxicity, brain disorders and epigenetics. Based on this research and fellowship training he has received several awards and honors, such as: Honorary doctor and honorary Professor in Pharmacology of the Polish Pharmacology Society, Sansone Award of the School of Medicine, University of Washington, St. Louis, Missouri. He is serving as an editorial member of twenty-four reputed journals like Neurotoxicity Research and Acta Neurologica Scandinavica & expert Reviewers for 117 journals like Psychopharmacology, European Journal of Pharmacology and Journal of Addiction Research and Therapy. He have authored 318 research articles, 150 book chapters, editored 42 books, and one general psychology book. He is a member of Neurotoxicity Society. He/she has honoured as Founding Member of European Behavioural Pharmacology Society.

Neurosciences,Psychiatry,Basic Medicine

Steven Benvenisti is a partner at one of the largest personal injury law firms in the United States of America, with offices in New York and New Jersey. For the past fivern(5) years, he has been included on the list of the National Trial Lawyers “Top 100 Trial Lawyers”.He is honored to be the Vice-Chairman of the Board of Directors forrnMothers Against Drunk Driving National and is also one of the directors of the Brain Injury Alliance. Steven has received over 30 awards, including a US CongressionalrnCitation, US House of Representatives Certificate of Special Congressional Recognition and “Citizen of the Year”. Steven authored Spring Break: A True Story of Hopernand Determination about a famous case he handled involving a severely brain injured college student who received long-term inpatient and outpatient acute care and rehabilitation. Spring Break credits the doctors, nurses and rehabilitation professionals for the wonderful work that they do in improving the lives of patients and their families.rnHe has been a keynote speaker at over 100 conferences and gladly donates 100% of his honoraria to charity.

Injury

Thomas E Nordahl M.D, PH.D is a professor emeritus at UV Davis school of Medicine. He did Psychiatry Residency from University of California, Davis. He worked as Junior staff at National Institute of Mental Health, Senior Clinical Fellow (NRSA), National Inst. Mental Health 1988-1989 Senior Staff Fellow, National Inst. Mental Health 1989-1995 Assistant Professor of Psychiatry, U.C. Davis Medical Center 1989-1991 Guest Scientist, Lawrence Berkeley Laboratory 1991-2003 Staff Scientist, Lawrence Berkeley National Laboratory 1991-1994 Staff Physician, (PET consultant) Palo Alto VAMC 1995-1999 Research Director, Napa State Hospital 2000-2001 Sabbatical at SRI -Department of Behavioral Neuroscience and Lucas MRS Center, Stanford University 1996-2002 Associate Professor, Psychiatry & Behavioral Sci, U.C. Davis Medical Center His Awards and Professional Societies include in 1965 Central Valley (California) Mathematics Quiz Finalist, 1966 California State Scholarship Finalist, 1971 NSF Student Trainee Grant, 1979 Summer Fellowship at Medical University of South Carolina,1986-1988 National Research Service Award, 1972- Member of American Mathematical Society, 1985- Member of American Association for the Advancement of Science, 1992 Member West Coast College for Biological Psychiatry, 1993- Member of Society for Nuclear Medicine, 1994- Fellow Canadian College of Neuropsychopharmacology, 1995- Member of Society for Biological Psychiatry,2013 – December Elected Member College: ACNP His service include 1973-1974 Graduate Curriculum Committee, U.C. Davis, Student Representative, 1975-1976 Member Computing Services Comm., Cal. State College, Stanislaus, 1979-1980 Student Government Rep., Medical Univ. of South Carolina,1984-1985 President Psychiatry Residents Association, U.C. Davis, 1986-1988 NIMH "PET" Representative to Nuclear Medicine,1990-1992 Assistant Training Director, U.C. Davis –Psychiatry, 1992-1994 Psychiatry Course Director Sophomore Medical Class, 1994-1994 Member School of Medicine Research Priority Committee, 1995-2000 Director of Neuroscience/Psychopharmacology course for interns, 1996-2000 Human Subjects Review Committee, 2005-2010 Human Subjects Review Committee,2009-2011 Soc. Biological Psychiatry Planning Committee for,2013 Apr Training Human Subjects Review Committee

Neuroscience

Dr. Pappolla's training included 3 complete medical residencies and 2 fellowships (Neurology, Clinical Pathology, Anatomic Pathology, Neuropathology, Pain Medicine), a PhD in human aging with a postdoc/sabbatical in molecular biology and over 20 years of academic practice. He holds active board certifications in these 5 areas (Neurology, Clinical Pathology, Anatomic Pathology, Neurology, Pain Medicine). Some of his research work is cited in several thousand textbooks worldwide, with many papers reaching from 300 to over 1000 citations in peer reviewed journals. His lab was among the first to identify evidence of oxidative stress in Alzheimer's disease brain. In collaborations with Dr. Larry Refolo, Dr Suzana Petanceska at the NIH, Dr. Daniel Zambon in Spain and others, we conducted groundbreaking research on hypercholesterolemia as an early risk factor for Alzheimer's disease. As a neuropathologist, he described several unique neuropathologic lesions including the colloid body of Parkinson's disease (later renamed "pale body") and the ubiquitinilated "dot like inclusions" in aged brains. One other important contribution was the development of neuroprotective drugs as potential therapeutic agents. He identified of several naturally occurring neuroprotective substances like indole-3-propionic acid and others. Dr. Pappolla served as a consultant for the National Institutes of Health in the United States including being a chartered member of numerous study sections for over 25 years and as a full professor or faculty at several medical schools (LSU New Orleans, Mount Sinai Medical School in New York City, University of Texas) where he taught Neurosciences to medical students and medical residents for over 20 years. Currently, he holds a hybrid academic-private practice position in the Houston area. Dr. Pappolla can be contacted at www.SMPSClinic.com

Neuropathology

He completed MBBCH very good with honors on Nov 1982 and completed Master of General Surgery in 1987.He did fellowship in the department of Neurosurgery in 1994.He did doctorate degree in Neurological surgery in 1994.and member congress of American Neurological Surgeons on 2000 He is the House officerin Ministry of Health Hospitals and Alexandria university Hospitals for one year from 1983 to 1984.He worked as physician in the Ministry of Health Hospitals from 1984 to 1987.He is Registrar of Neurosurgery in private hospital from 1987 to 1988.He is Assistant lecturer of Neurosurgical department of Alexandria University Hospitals from 1988 to 1994.He is chief consultant of Neurosurgery in Saqr Hospitals, UAE from 2000 to 2003.He visit to Neurological surgery department, Royal College of Medicine,London in 2001. He is working as Professor of Neurosurgery department at Alexandria University from 2010 to till date.

Neurology and Neurosurgery

Academic background: 1956-1960 The Hebrew University, Jerusalem M.Sc. Physiology, 1960-1966 The Hebrew University, Jerusalem Ph.D. Neurophysiology 1966-1968 Johns-Hopkins Univ., Baltimore Post Doc. Biomedical Engineering Previous employment: 1981- 2003 The Hebrew University, Jerusalem. Professor Neurophysiology 2003- 2014 Bar-Ilan University, Ramat-Gan Professor Neurophysiology 1973 - 1981 The Hebrew University, Jerusalem Assoc. Prof. Neurophysiology 1969 - 1973 The Hebrew University, Jerusalem. Senior Lect. Neurophysiology 1968 - 1969 The Hebrew University, Jerusalem Lecturer 1966 - 1968 Johns Hopkins Univ., Baltimore Post doc. Biomed. Eng. Administrative appointments: 2003 - 2012 Director, Gonda Multidisciplinary Brain Research Center, Bar-Ilan University 2003 – 2004 Add-hoc committee on Computational Neuroscience, BMBF, Germany 1996 – 1999 Director, Life-Sciences division of the Israel National Science Foundation. 1992 - 1999 Director, The Interdisciplinary Center for Neural Computation. 1984 - 1994 Director, The Israel Center for Psychobiology. 1977 - 1980 Director, The Israel Center for Psychobiology. 1974 - 1977 Chairman, Department of Physiology. Honors: 1968 Back prize for 3 papers on excitability of EEG synchronizing and desynchronizing neurons. 1971 I.A.P.I. First prize for work on "Computer aided analysis of nerve cell activity". 1980 Dr. Mona and Dr. Ernest Spiegel Chair of Neurophysiology 1980 Visiting professor, Universite de Lausanne 1986 Visiting professor, University of Pennsylvania 1986 Johns Hopkins Society of scholars 1996 Teva founders prize for outstanding work in brain research 1997 Miller visiting professor, UC Berkeley, USA 2004 Emet (Prime Minister of Israel prize), Israel 2012 Valentino Braitenberg's Golden Neuron award

Neurophysiology

Education: He did his M.D Neurosurgery from Alexandria University from 1980-1986 He did his M.sc General surgery from Alexandra University from 1977 to 1980 Experience: He worked as General secretary at Annual Conference of the Department of Neurosurgery,Alexandria University at Egypt in 2009. He worked as General secretary at Annual Meeting of the Spine Conference of the Department of Neurosurgery at Alexandria University, Egypt in 2008 and 2009. He is presently Board Member of Egyptian Society of Neurosurgery, Egypt. He is a Member of American Congress of Neurosurgery from 1991. He attended Conferences such as Egyptian Society of Neurosugery Annual Conference etc. Awards and Honors: He received Scientific Activity Award of the Egyptian Society of Neurosurgery,2007. Hi received Scientific Excellence Award of Assult University, 2005. He received Appreciation Award of the Egyptian Society of Neurosurgery,2000

Neurosurgery

Elena Paley has a PhD degree in molecular biology. Dr. Paley is a solo inventor of the metabolic model of neurodegeneration induced by biogenic amine tryptamine. The projects of Dr. Paley focus on alterations of protein biosynthesis machinery in neurodegeneration and human gut microbial-host interactions in Alzheimer’s disease. Dr. Paley is a founder and co-founder of Expert Biomed, Inc. and Stop Alzheimers Corp. The projects are conducted in collaboration with Harvard University, Brandeis University, University of Miami, University of Texas at San Antonio and more.

Alzheimers disease and Neurodegeneration

Dr.Sandeep Singh is a Neurobiologist with a strong background in Biochemistry and Biomedicine. He has dedicated more than 7 years to Neuroscience Research and used animal models system to investigate the therapeutic potential for Alzheimer’s disease using synthetic as well as natural compounds in Drosophila model system. After obtaining his M.Sc. degree in Biotechnology, he completed his Ph.D. from Department of Biochemistry, Institute of Science, Banaras Hindu University then moved to the Department of Neurobiology, The University of Chicago, IL, USA and worked on the role of microbial immune responses in AD pathogenesis. Currently, he is the Founder President of a non-profit organization in India named Indian Science Education and Technology Foundation (ISET Foundation) and working in the field of Science and Technology Promotion (Neurobiology and Biotechnology Research Promotion). The last 7 years research work come up with a couple of nice publications to his credit in journals of international repute like (International Journal of Alzheimer’s Disease, Neurotoxicity Research, Oxidative Medicine and Cellular Longevity, BBRC, Neurochemical Research, Neuroscience Letter, Current Drug Metabolism etc.) and 2 book chapter as mentioned in his CV. He is Member of the editorial board of several International neuroscience related journals. Also a member of several scientific societies like INDIAN ACADEMY OF NEUROSCIENCES, ALZHEIMER’S AND RELATED DISORDERS SOCIETY OF INDIA, American Academy of Neurology, International Society of Neurochemistry, Member of American Society of Neurochemistry.

Alzheimer’s Disease, Neurotoxicity Research, Oxidative Medicine and Cellular Longevity, BBRC, Neurochemical Research

Dr.Sandeep Singh is a Neurobiologist with a strong background in Biochemistry and Biomedicine. He has dedicated more than 7 years to Neuroscience Research and used animal models system to investigate the therapeutic potential for Alzheimer’s disease using synthetic as well as natural compounds in Drosophila model system. After obtaining his M.Sc. degree in Biotechnology, he completed his Ph.D. from Department of Biochemistry, Institute of Science, Banaras Hindu University then moved to the Department of Neurobiology, The University of Chicago, IL, USA and worked on the role of microbial immune responses in AD pathogenesis. Currently, he is the Founder President of a non-profit organization in India named Indian Science Education and Technology Foundation (ISET Foundation) and working in the field of Science and Technology Promotion (Neurobiology and Biotechnology Research Promotion). The last 7 years research work come up with a couple of nice publications to his credit in journals of international repute like (International Journal of Alzheimer’s Disease, Neurotoxicity Research, Oxidative Medicine and Cellular Longevity, BBRC, Neurochemical Research, Neuroscience Letter, Current Drug Metabolism etc.) and 2 book chapter as mentioned in his CV. He is Member of the editorial board of several International neuroscience related journals. Also a member of several scientific societies like INDIAN ACADEMY OF NEUROSCIENCES, ALZHEIMER’S AND RELATED DISORDERS SOCIETY OF INDIA, American Academy of Neurology, International Society of Neurochemistry, Member of American Society of Neurochemistry.

Alzheimer’s Disease, Neurotoxicity Research, Oxidative Medicine and Cellular Longevity, BBRC, Neurochemical Research

Ricardo B. Maccioni M.D., Ph.D. is a Professor of Neurology at the Medical School, and Professor of Neurosciences, University of Chile. He also serves as the Director of the Laboratory of Molecular Neurosciences, Scientific Director of the International Center for Biomedicine (ICC) and Senior Investigator of the Brain/Mind Program in Chile. He has served as Associate Professor at the University of Colorado Medical School, Denver, U.S.A. He received his doctoral degree in 1975, and was a postdoctoral fellow at the National Institutes of Health, the University of Colorado Health Sciences Center and a visiting scholar at and the Max Plank Institute for Biophysics in Germany. He is a world class scientist that has made some of the world leading contributions to the cell biology of neuronal cells and the study of Alzheimer’s disease. His discoveries on the role of tau protein in the pathogenesis of this disease, his neuroimmunomodulation theory of neurodegenerative disorders, the design of a new in vivo neuroimaging technology, novel biomarkers for its early diagnosis and innovative approaches for the treatment of this disease, are among his major contributions. On the basis of these and numerous other findings, he is considered among the leading investigators in Alzheimer´s disease. Dr. Maccioni was ranked among the three Chilean scientists with the highest impact factor in a recent study on science productivity. He has served as Associated Editor of the Journal of Alzheimer´s Disease, and the board of J. Alzheimer´s Reports, Journal of Neurochemistry, Therapeutic Advances in Chronic Diseases, Frontiers in Dementia and Archives of Medical Research. He is co-author with George Perry of the recent book “Current Hypotheses and Research Milestones in Alzheimer´s Disease”, among other 10 books in this medical field. Maccioni has made outstanding achievements in the training of 59 young scientist, and is the author of 146 publications in high-impact journals and 18 patents. His scientific findings are characterized by the innovative approaches to elucidate complex problems of modern medical research. He has received more than sixty research grants and several international prizes, including awards from the Alzheimer´s Association, the Milheim Foundation, Presidential Chair in Science, Chacellor´s medal of the University of Chile, and Doctor Honris causa at several universities. His leadership is further attested by being the founder of IMBO (Ibero-American Molecular Biology Organization), the Millennium Institute CBB, and the International Center for Biomedicine, a world class center of excellence. He has organized over forty international conferences with prominent neuroscientists from all over the world.He is a also member of the Innovation Circle of ICARE in Chile, the National Academy of Sciences, Scientific Director of Neuroinnovation and advisor for several important scientific institutions. He is also an elected member of the Danna Alliance for Brain Inititives.

In the field of technological innovation he has made contributions in monitoring new molecules for the treatment of Alzheimer´s disease.

Federico Ortiz-Moreno received a Bachelor's degree in psychology from the University of Monterrey, with emphasis in the Social Area He is Journalist and Columnist of some newspapers in Monterrey, Mexico, as well as a contributor of various magazines and newsletters, both national and international.He has received two Literature and Arts Diploma Awards. He has been a contributor to BBC London.He has been author of several books of short stories and poems, translated into four languages.He has been a founding member and first President of the Alzheimer's Association of Monterrey.He has been former President of the Mexican Federation of Alzheimer's disease.In 2010, Member of the Governance Committee of the Alzheimer's Disease International (ADI) based in London.He has participated as a speaker in more than 20 countries, and has contributed to the formation of several support groups and associations, both national and international level.Director and coordinator of the newsletter called “Alzheimer para todos”.He has been author of more than 250 articles of topics cultural and more than 100 about Alzheimer's with translations into various languages. He has received the National Award for volunteer Mexican 2007 by SEDESOL (Minister of Social Development in Mexico)Special Award “45 stories of success” by the Universidad de Monterrey, in 2014.Member of National Geographic Society He has been benefactor members of the Real Academia Española.

Alzhiemers disease

Dr.Howard Federoff has joined University of California, Irvine as Vice-Chancellor for Health Affairs and Dean of the Shool of Medicine.Federoff comes to UC Irvine from Georgetown University,where he served as Excecutive Vice president for Health services and Excecutive dean of the school of Medicine.Dr. Federoff received his MS, phD and MD degrees from the Albert Einstein college of Medicine,and did his Internship, Residency and Fellowships at Massachusetts General Hospital/Harvard Medical School.

Dr.Federoff's research intrests include Gene theraphy and neurodegenerative diseases such as Prakinson's, Alzhiemer's and Prion diseases; he holds number of medical patents with number of other patents pending.His Research has received support from the National Science Foundation,National Institutes of Health, and the U.S department of Defence.He is widely published and has served as a reviewer for many Journals including Brain and Mind,Experimental neurology and Gene theraphy.

Aage R. Møller, PhD (D. Med. Sci.) is Professor of Cognition and Neuroscience and Endowed Chair in the School of Behavioral and Brain Sciences at the University of Texas at Dallas. He is the Chairman of the Institutional Review Board at the University of Texas at Dallas as well as the Chairman of the Board for the Tinnitus Research Initiative Foundation. He has done extensive research on tinnitus and has had a significant role in the development of neurophysiological monitoring.Dr. Aage Møller is known internationally for his innovative research on sensory systems and neural plasticity and for developing methods for reducing the risk of neurological deficits in neurosurgical operations.When Dr. Møller joined UT Dallas 1997, he became interested in abnormalities in the nervous system function among individuals with autism. He developed teaching programs in the biology of pain; sensory systems, neuroplasticity and he established the first university program in teaching IONM in a graduate program. During his time at UT Dallas, he was named the university’s “President’s Teaching Excellence Award,” won Teacher of the Year for the School of Behavioral and Brain Sciences, and was named distinguished lecturer in Cognition and Neuroscience. Dr. Møller earned his PhD in medical science at the Karolinska Institute in Stockholm, Sweden.My most recent book is "Neuroplasticity and its Dark Sides: Disorders of the Nervous System". I have been editor or co-editor of seven published books, most recently, "Textbook of Tinnitus", published by Springer 2010, 95 chapters and 785 pages. One of my books have been translated to Japanese and two have been translated to Chinese. I am the author or co-author of more than 200 articles in refereed journals, more than 100 book chapters. I was Editor-in-Chief (and founder) of the international journal, Hearing Research for 27 years (1978-2005); I am member of the Editorial Board of many other international journals. I am interested in teaching and I have developed new courses and have been writing books that are used in teaching. At The University of Texas I have developed courses such as "Biology of Pain", "Sensory Systems", "Neural Plastic and Disorders of the Nervous System", "Functional Human Neuroanatomy" and Intraoperative Neurophysiological Monitoring" that I teach in the Neuroscience Program of the School of Behavioral and Brain Sciences.

Aage R. Moller research intrests include function of middle ear and the cochlea, then the neuroscience of the auditory system, somatosensory and visual systems and of hyperactive motor disorders. He have used systems identification methods such as Winer kernel analysis of recordings from single nerve cells in the cochlear nucleus using pseudorandom noise stimuli. He is particularly interested in the role of neuroplasticity in disorders such as severe tinnitus, chronic neuropathic pain and spasticity and muscle spasm. He have also studied the role of the non-classical auditory pathways and their involvement in disorders such as tinnitus.

UC Irvine neurologist Arnold Starr, MD, PhD, a longtime chair of the Department of Neurology, has been selected as an honorary member of the American Academy of Neurology.Starr was the second neurologist to join the UC Irvine faculty and became the first chair of the Department of Neurology. He led the division of neurology, as it became a new department in 1977. He remained chair for 10 years. Although retired, Starr continues to teach and conduct research.“Dr. Starr is a wonderful example of the best that neurologists can achieve in their lifetimes,” said Steven L. Small, PhD, MD, Stanley van den Noort Professor and current chair of the department. “In retirement, Dr. Starr continues to be active in teaching and research.” The AAN bestows honorary membership upon those individuals deemed by the Academy’s board of directors to have performed exceptional meritorious contributions to the field of neurology, with national or international impact.

Arnold Starr research intrests include Neurological disorders affecting cognition, sensation and motor behaviors. He is investigating the neurobiological bases of clinical disorders of the nervous system that affect sensation, motor performance, and cognition. His studies employ electrophysiological and behavioral methods to define functional mechanisms underlying clinical syndromes relevant for specific research question. The current interests are two fold:1) Hearing disorder called Auditory Neuropathy and 2) Memory changes in Aging and Dementia

Dr. Pant received his M.A. and Ph.D. degrees in Physics from Agra University, Agra, India. His postdoctoral studies were conducted on the mechanisms of electron and ion transport in model membrane systems at the Department of Biophysics at Michigan State University. He joined the Laboratory of Neurobiology in the NIMH as a senior staff fellow in 1974 with Dr. Ichiji Tasaki where he studied the function of the axonal cytoskeleton in the squid giant axon. In 1979 he moved to the NIAAA extending his studies on the neuronal cytoskeleton and the effects of alcohol on its regulation. Dr. Pant moved to the NINDS, Laboratory of Neurochemistry in 1987 where he is presently chief of the section on Cytoskeleton Regulation. His laboratory is studying the mechanisms of topographic regulation of neuronal cytoskeleton proteins by post-translational modification, including the role of kinase cascades in normal brain and during neurodegeneration.

The major focus of this laboratory has been to study the mechanisms of topographic regulation of neuronal cytoskeletal proteins regulation by phosphorylation and neurodegeneration. In a normal physiological state, cytoskeletal proteins are phosphorylated extensively in the axonal compartment of a mature neuron. Although all the substrates, kinases, phosphatases and their regulators are synthesized in neuronal cell bodies, little or no cytoskeletal protein phosphorylation has been detected in the cell body compartment. Under a variety of neuropathological conditions, however, such as ALS, Alzheimers Disease, or Picks disease, hyperphosphorylation of these molecules has been found in abnormal aggregates within cell bodies, usually correlated with massive neuronal cell death. The mechanisms underlying these profound compartmental shifts in neuronal phosphorylation are not well understood.The normal physiological processes within neurons are controlled by signal transduction mechanisms that regulate the balance between protein kinase and protein phosphatase activities. We have shown that the most abundant and extensively phosphorylated motifs in the c-terminal domains (lys-ser-pro-, or KSP) are primarily phosphorylated by proline directed kinases, cdk5 and MAP kinases. Moreover, we have demonstrated that this phosphorylation is due to activation of the signal transduction cascade. Recently, we have focussed on the other part of this regulation, the protein phosphatases. The other project is to study the expression, regulation and role of neuronal Cdk5 in nerve cell function.Cdk5 is a unique multifunctional kinase. Unlike other cyclin-dependent kinases, it is expressed predominantly in post-mitotic neurons, its activity modulated by association with nervous system-specific propeins. Since its identification and characterization in our laboratory, we have been intensively studying its mechanisms of regulation and its role in nerve cell function.

Stephen D. Skaper received a PhD in biochemistry from the University of South Dakota and Laurea in chemistry from the University of Padua, Italy. He is currently Adjunct Professor in the Department of Pharmaceutical and Pharmacological Sciences (section on Pharmacology and Anesthesiology) at the University of Padua. From 1998-2008 he was a Senior Group Leader for Neurodegeneration Research, Neurology & GI Centre of Excellence for Drug Discovery, GlaxoSmithKline Research and Development Limited, United Kingdom. Prior to that he held academic research positions in the Department of Biology at the University of California, San Diego. Dr. Skaper has authored/co-authored over 300 research papers, book chapters and monographs, as well as having guest-edited six journal thematic issues and a volume of Methods in Molecular Biology on neurotrophic factors. He is Editor-in-Chief of CNS & Neurological Disorders Drug Targets, the Associate Editor of the American Journal of Neuroprotection and Neuroregeneration, and a Councillor of the International Association of Neurorestoratology. His research interests focus on the role of immune cells and their interactions in neuroinflammation, in particular with regards to neuropathic pain and autoimmune demyelinating diseases like multiple sclerosis, and the development of therapeutic strategies based on natural molecules. He is a member of Sigma I, Phi Lambda Upsilon, Alpha Chi Sigma, the Society for Neuroscience and the International Society of Cerebral Blood Flow and Metabolism.

Molecular biology and cellular mechanisms of cell death in CNS aging, neurodegenerative disorders and neuroinflammation, astrocyte-microglia interactions, pharmacological modulation of oligodendrocyte precursor maturation and demyelinating diseases. Track record of drug discovery project leadership in kinases, ion channels, G-protein-coupled receptors, DNA repair enzymes, growth factors, identification and optimization of tools for target validation studies, utilising RNAi, conditional and viral knockdown\outs\ins, transcriptomics, proteomics and in vitro cell-based disease or mechanism relevant assays in rodent systems.

Hsien-Yuan Lane is distinguished Professor and Director of Graduate Institute of Biomedical Sciences, College of Medicine. He is the Director, Department of Psychiatry, College of Medicine. HY Lane received Ph.D. from National Defense Medical Center (Taiwan) in 2000 and he received M.D from Taipei Medical University (Taiwan) in 1987. HY Lane Academic distinctions include Y.Z. Hsu Scientific Paper Award, Biotechnology Category, Taiwan in 2006, The 10th National Innovation Award, Taiwan in 2013, The 24th Wang-Ming-Ning Award, Taiwan in 2014 Ministry of Science and Technology Outstanding Research Award, Taiwan in 2014 CNS Drug Innovation Award and The International of College of Neuropsychopharmacology 2016

Hsien-Yuan Lane is distinguished Professor and Director of Graduate Institute of Biomedical Sciences, College of Medicine. He is the Director, Department of Psychiatry, College of Medicine. HY Lane received Ph.D. from National Defense Medical Center (Taiwan) in 2000 and he received M.D from Taipei Medical University (Taiwan) in 1987. HY Lane Academic distinctions include Y.Z. Hsu Scientific Paper Award, Biotechnology Category, Taiwan in 2006, The 10th National Innovation Award, Taiwan in 2013, The 24th Wang-Ming-Ning Award, Taiwan in 2014 Ministry of Science and Technology Outstanding Research Award, Taiwan in 2014 CNS Drug Innovation Award and The International of College of Neuropsychopharmacology 2016

Üsküdar University Founder and Rector of Turkey's first NPISTANBUL neuropsychiatry hospital, which carries out the Brain Hospital Chairman of the Board of Directors. There are more than 100 publications, 31 of which are international.

Neuropsychology

KHASHAYAR PAZOOKI GROUP PSYLUX S.A / NEUROACADEMY LUXEMBOURG Specialized in neuro biology, neurophyschology, clinical psychotherapy sciences and neurocognitive sciences. Head of research department at Group Psylux. S.A (www.psylux.eu), member of the scientific committee of AVM-Luxembourg, head of Traumainstitut Luxembourg (www.traumainstitut.lu) and neuroacademy Luxembourg (www.neuroacademy.lu) , lecturer at different institutes such as AAP-Wien, MSK-Cario, Keyspeaker at World Food Programme (WFP) in Madrid, guest lecturer at Sigmund Freud Private University in Vienna.

Neurology

Mohamed FAhmy Zeid completed completed Master of General Surgery in 1988 and pursued his fellowship in the department of Neurosurgery in 1994.He earned doctorate degree in Neurological surgery in 1994. He was the House officer in Ministry of Health Hospitals and Alexandria university Hospitals for one year from 1983 to 1984.He worked as physician in the Ministry of Health Hospitals from 1984 to 1987.He is Registrar of Neurosurgery in private hospital from 1987 to 1988.He is Assistant lecturer of Neurosurgical department of Alexandria University Hospitals from 1988 to 1994.He is chief consultant of Neurosurgery in Saqr Hospitals, UAE from 2000 to 2003.He visited to Neurological surgery department, Royal College of Medicine,London in 2001. He is working as Professor of Neurosurgery department at Alexandria University from 2010 to till date and he is the Founder & President of Brain & Skull Egyptian Society from Last October 2017.

Neurosurgery

Dr. Wendel-Mitoraj is CEO and Founder of BrainCare Oy (Ltd). She obtained her BSc in Electrical Engineering and then worked for Samsung Austin Semiconductor (Austin, Texas, USA) as a photolithography engineer. After relocating to Tampere, Finland, she earned her doctorate in computational modeling of EEG electrodes. During her post-doctoral tenure, she designed and patented the electrode strips and developed the BrainCare concept. She negotiated and acquired for BrainCare Oy the intellectual property assets developed at Tampere University of Technology (Tampere, Finland). She strategically focused on bringing SOENIA™ Epilepsy Diary and Cloud as a first medical device compliant product to the market. Her current focus is bringing the novel electrode to the market.

Neurology

Dr. Ahmad Tamimi Started his study at University of Oviedo graduating as Medical Doctor in 1977, he got his training in Neurosurgery at General Hospital of Asturias, Spain as from 1977-1981, he had his PhD in Medicine from University of Oviedo, Spain, in 1981. He worked as a consultant at General Hospital of Asturias as from 1981until 1984, consultant at General Hospital of Las Palmas as from 1984 until 1990, and consultant at Jordan University Hospital since 1990 till present. He was appointed as Chairman of Neurosurgical Department as from 2000 until 2013. In 2000, he became a full professor of Neurosurgery. Prof. Tamimi became a Dean of Medical School at Muatah University during the period from 2005-2007.and General Director of Jordan University Hospital from 2013-106. Member of the scientific committee the Arab Board in Neurosurgery and Member of the scientific committee Jordanian Board scientific committee member in Neurosurgery. Special interest in Neuro-oncology and epilepsy surgery. He is the author of over 150 publications in Neurosurgery, Medical Ethics , Medical Education and Health care system.

Neurosurgery

Prof. Dr. Heyam Saad Ali, M. Pharm., and Ph-D from UoK. She is working as a head of the pharmaceutics department in Dubai Pharmacy College, UAE. Prof. contributed more than 70 articles to reputed international scientific journals and conferences, in different conventional, controlled and targeted drug delivery systems in pharmaceutical product development. She has been invited as a speaker at numerous International conferences. Reviewer and member of the editorial board of many international journals.

Pharmacy

Humberto Mendes Faria Rodrigues Bachelor and Master in Clinical and Health Psychology at Aveiro University (Portugal) and internship in Coimbra Hospital University Centre (e.g., Intervention in Sleep Disorders and Pain Disorders). Later, worked as a psychologist and neuropsychologist. Also performed a research project in Biofeedback/Neurofeedback by the Foundation for Science and Technology (FCT). Is currently working with the Institution of Solidarity Projecto Homem / Braga in the addictions field and he is part of the research group of StressLab of the University of Aveiro . In parallel, also conducts outpatient consultations in various psychological disorders. Concomitantly, made several national and international communications in various Congress as Guest Speaker in the field of Neuroscience. Editor in Chief and Founder of the International Journal of Psychology and Neuroscience and Editor in several Scientific Journals and Author of various articles in peer review journals. At the moment, is a Ph.D. student in Neuroscience at the Faculty of Medicine, University of Salamanca – Neurosciences Institute of Castilla y León. Research interests: Experimental Psychology, Neuropsychology and Biological Rhythms, particularly in: Assessment and Neuropsychological Rehabilitation, Drug Abuse and Addiction, Behavioural Neuroscience, Behavioural Management, Biofeedback/Neurofeedback, Sleep Disorders, Pain Disorders.

Psychology

Sam Vaknin is Visiting Professor of Psychology, Southern Federal University, Rostov-on-Don, Russia and Professor of Finance and Psychology in CIAPS (Centre for International Advanced and Professional Studies). Sam Vaknin is the author of Malignant Self-love: Narcissism Revisited and other books about personality disorders. His work is cited in hundreds of books and dozens of academic papers. He spent the past 6 years developing Cold Therapy: a treatment modality for Narcissistic Personality Disorder (NPD). Over the years, with dozens of volunteers, he found that it was effective with clients suffering from a major depressive episode as well.

Personality disorders

Dr. Alexandru J. Graur, Ph.D., Former Project Associate , The Hong Kong Polytechnic University, School of design, Digital Media. Former Associate professor, University of Turin, Italy (Post graduate School in Health Psychology), Department of Psychology. Dr. Graur specializes in composition, musicology and clinical music therapy. He received a graduate degree in Composition-Musicology and is a diplomat in Medicine (P.A.P. - Physician Assistant in Psychiatry). Since 1978, Dr. Graur has implemented the Music Integrative NeurotherapyTM, an applied Neuroscience method combining Music, Psychiatry, Molecular Biology and Quantum Mechanics. Dr. Graur has had a long career as a soloist, orchestra conductor and composer (classical music) with performances and broadcasts of his works in Italy, Germany, Romania, Switzerland and the U.S. and is a recipient of a numerous national and international prizes for interpretation and composition. . He has presented numerous workshops and seminars to audiences in Italy, China, Sweden, South Korea and the U.S.A.

Musicology and clinical music therapy.

Dr. Reza Nejat is an Iranian Board certified Anesthesiologist and Fellow of Critical Care Medicine. After graduating from Tehran University of Medical Sciences (TUMS) as a general practitioner, he could achieve the ECFMG certification and, upon being admitted in Anesthesiology Residency Programme at Iran University of Medical Sciences, he could pass Board Certification exam successfully in Anesthesiology. Passing the fellowship programme in Critical Care Medicine (CCM) at Sina Hospital, TUMS, he, as a fellow of CCM, is now the chief of CCM Department at Bazarganan Hospital in private-sector. During this period he was inclined to study molecular medicine in the field of sepsis, acute heart failure and neuro-critical care. Administration of EPO to neurologically injured patients has been one of his field of interests and experience for the past 4 years. He was the chief of few hospitals prior to working as an assistant professor at Shahid Beheshti University of Medical Sciences, as an anesthesiologist and also as a fellow of CCM, from 2010 to 2015. Dr. Nejat has published four books in the fields of cardiology, nephrology, fluid and electrolyte, nutrition, metabolism and endocrinology. Recently, he contributed to the chapter of “Acute Heart Failure” in the reference book “Comprehensive Textbook of Therapeutics” studied by post-doc residents of pharmacotherapy

Neurology

Sylvain Doré, PhD is a Professor and Program Director of Research Operations in the Department of Anesthesiology, as well as Professor of Neurology, Psychiatry, Pharmaceutics, and Neuroscience, at the University of Florida, College of Medicine. Dr. Doré attained his PhD, in biomedical science, from the University of Montreal and an MS degree in pharmacology at the University of Quebec. He received post-PhD training in psychiatry at McGill University, as well as post-PhD training in neuroscience at Johns Hopkins University. Dr. Doré’s research pertains to studying new effective mechanisms that limit neuronal dysfunction associated with ischemic and hemorrhagic stroke, Alzheimer disease (AD), aging, and various other neurological disorders. His objective is focused on understanding the protective role of heme metabolites in the brain using cellular/molecular techniques and various models of stroke, Alzheimer disease, and aging. New knowledge is gained specifically, by investigating the action and the role of activity of the heme oxygenase enzyme and its unique bioactive metabolites, namely, carbon monoxide, iron, biliverdin, and bilirubin. His overall goal is to slow down the progression of the disease, and ultimately stop it.

Neurodigenerative disorders, ischemic stroke, Alzheimer’s disease, aging, heme oxygenase, prostaglandins.

Dr. Bradley S Duhon is a Neurosurgery Specialist in Parker, Colorado. He graduated with honors from University Of Texas Medical School At Houston in 2004. Having more than 13 years of diverse experiences, especially in NEUROSURGERY, Dr. Bradley S Duhon affiliates with many hospitals including University Of Colorado Hospital Authority, Parker Adventist Hospital, and cooperates with other doctors and specialists in many medical groups including University Physicians Incorporated, Neurosurgical And Spine Specialists. He is currently a member of Congress of Neurological Surgeons (CNS) and American Association of Neurological Surgeons (AANS).

Neurological Surgery, Spine Surgery

Dr. Bryan E Kolb completed his PhD degree from Pennsylvania State University. . Dr. Kolb received a Queen’s Diamond Jubilee Medal from Royal Society of Canada at 2013. Kolb was awarded a Killam Fellowship from the Canada Council and is a Fellow of the Royal Society of Canada. He is a former President of the Canadian Society for Brain, Behavior, and Cognitive Science and former President of the Experimental Division of the Canadian Psychological Association. He is currently a member of the Canadian Institute for Advanced Research’s program in Child and Brain Development. Bryan Kolb has published 5 books, including two textbooks with Ian Whishaw (Fundamentals of Human Neuropsychology, 7th Edition; Introduction to Brain and Behavior, 4th Edition), and over 350 articles and chapters.

Brain plasticity and behavior. Bryan Kolb’s research focuses on how neurons in the cerebral cortex change in response to experiences, drugs, hormones and injury, and how these changes influence behaviour. Over the past 40 years he has identified the ‘rules’ that govern the effects of cerebral injury at different developmental ages. His work has fueled new treatments to help victims of cerebral injury. Kolb was the first to demonstrate how new brain cells grow to restore cerebral function both in development and adulthood and the first to show (with Terry Robinson) that psychoactive drugs produce permanent changes in neuronal structure in cerebral structures and that these changes influence later brain plasticity.

Dr. Kim-Tenser is board certified in neurology, vascular neurology, and neurocritical care. She specializes in the diagnosis and management of patients with stroke and those who are neurocritically ill requiring admission into the neurosciences ICU (ie: GBS, SE, myasthenic crises, SAH, ICH, AVM's, spinal cord injury.

Dr. Kim-Tenser's research interests include the management of intracerebral hemorrhage, stroke outcome/genetics, subarachnoid hemorrhage, hypothermia, and neuroprotection in stroke.

Dr. Adham S Kamel is a Neurology Specialist in the diagnosis and treatment of diseases or impaired function of the brain, spinal cord, peripheral nerves, muscles, autonomic nervous system, and blood vessels that relate to these structures based at Syracuse, New York. He graduated with honors in 1996 at Medical School: Cairo University, Egypt. Having more than 21 years of diverse experiences, especially in NEUROLOGY, Dr. Adham S Kamel affiliates with many hospitals including University Of Texas Medical Branch, Auburn Community Hospital. He had done his neurology residency at Allegheny General Hospital, Pittsburgh PA. His specialties are neurology, vascular neurology, electrophysiology EEG.

Stroke, Interventional Neurology, Stem cell

Wuwei (Wayne) Feng completed neurology residency training at MUSC, followed by a stroke fellowship at Beth Israel Deaconess Medical Center/Harvard Medical School. He is board certified in general neurology as well as stroke neurology, and is specialized in young stroke diagnosis and management, stroke recovery, and rehabilitation. Additionally, Dr. Feng runs a first of its kind clinic in South Carolina - Post-Stroke Spasticity Clinic. Dr. Feng's research focuses on stroke motor recovery and his research is funded by NIH, AHA as well as industry. He is the stroke rehabilitation award winner from international Stroke Conference 2015 and the Franz Gerstenbrand Award winner from World Federation of Neurorehabilitation 2016. He has published numerous papers and has presented his research at regional, national, and international conferences. His philosophy on stroke care is "We will work together to get you better and stroke free."

Stroke rehabilitation and recovery including spasticity management, Stroke in middle age population (diagnosis, management and recovery), Tele-stroke consultation

Mr. Alejandro De la Parra Solomon is an entrepreneur focused on Information Technology, Education and Health. He is creative and results-driven and has 16+ years of Digital Strategy experience in architecture and implementation. Mr. De la Parra is the COO and Co-founding Partner at The Solomon Brokerage Firm. He currently leads as CEO at Mass Media Dynamics and De la Parra Mobile Solutions and is former CEO & Founder at Astrum Salud Móvil and its Telemedicine service Astrum Móvil. Moreover, he is COO & Co-founder at RegenerAge® Clinic & RegenerAge® Beauty, the Digital Strategy Director & Co-founder at Dr. Jois®, BiorganicAging®, What Skin Needs™/WSN International Pty. Ltd. He also serves as current CMO at ReAnima Advanced Biosciences and is the Digital Media Director at Bioquark, Inc. He is also the former Latin America Region Manager and Digital Strategy adviser at CardiacSense and former CITO & Senior Partner at Cerezo Editores. Within the academic and educational fields, Mr. De la Parra is a Senior Partner, Executive Vice President: Executive Chairman of the WAMS Mobile Health Division, WAMS Chief Coordinating Officer, Member of the WAMS Executive Council (WAMS Executive Board), Member of the WAMS Education & Training Board (ETB), Member of the WAMS Editorial Board, Honorary Member of the Academy Faculty FWAMS, WAMS Digital Strategy Chairman & Fellow of the Academy. Moreover, Mr. De la Parra acts as the Chief Operating Officer and is a Co-founding Partner at The Reprogramming Medicine Association. Mr. De la Parra is also a member of the National Introducing Brokers Association and a part of the National Biofuel Board, (Alliance Program), also being the founder and former Board of Directors member of Astrum Fundación, an Advisory Board member of the Lifeboat Foundation, an Advisory Board member of the Future Worlds Center - Cyprus Neuroscience & Technology Institute (Senior TV Program), a Federated member of the International Longevity Alliance, and volunteered as Digital Strategy adviser at the Major Mouse Testing Program. He is also a member of the Web Committee at the Life Extension Advocacy Foundation / Lifespan.io and has volunteered with SENS Research Foundation for the OncoSENS Program in Digital Strategy.

Cell Regeneration, Biosciences

Dr. Vijay K Sharma is the current recipient of the prestigious Clinician Scientist Award from National Medical Research Council, Singapore. He has published 187 peer reviewed scientific papers and 19 book chapters. Dr. Sharma is Associate Editor for BMC Neurology and serves on the editorial boards of many scientific journals including Stroke, Journal of Stroke, Neural Regeneration Research, Recent Patents on Medical Imaging, Journal of Behavioral and Brain Science, World Journal of Hypertension, ISRN Neurology, American Journal of Cardiovascular Diseases, World Journal of Neurology, Journal of Neurology & Translational Neuroscience (JNTN), International Journal of Medical Sciences and Biotechnology, Advances in Neuroscience Research and Neurological Research and Therapy.

Thrombolysis in acute stroke, especially sonothrombolysis, Blood pressure management in acute ischemic stroke, Advanced applications of transcranial Doppler in cerebrovascular diseases, Intracranial stenosis, Assessment of cerebral hemodynamics with cerebrovascular ultrasonography.

Dr Girouard completed her PhD in cardiovascular physiology in 2002 at the Université de Montreal under the supervision of Dr J. de Champlain, a specialist in the field of hypertension. She then pursued with two fellowships both on the study of cerebrovascular regulation: one at the Weill Medical College of Cornell University and a second one at the University of Vermont under the supervisions of Dr. Costantino Iadecola and Dr Mark T. Nelson, respectively. She is now associate professor at the Department of pharmacology and physiology at the Université de Montréal and the director of the laboratory of neurovascular pharmacology since 2008. Along her career, Dr Girouard received prices including the Merck New investigator price of the ‘Société Québécoise d’Hypertension Artérielle’ and the Young Investigator Award from the Heart and Stroke Foundation of Canada. She recently was nominated Fellow of the American Heart Association. She is involved in many Societies related to Hypertension and neurosciences in particular the ‘Société Québécoise d’Hypertension Artérielle’ and the ‘International Society of Cerebral Blood Flow and Metabolism’ in which she is member of the Board of Directors.

The research interests of Dr Girouard are the study of the mechanisms underlying cerebrovascular regulation in health and diseases especialy in the context of hypertension and arterial stiffness. The main objective of her research is to find therapeutical targets to protect the brain from vascular diseases. To reach this objective, she is using various techniques from molecular biology to brain imaging in mice and humans. She published mostly in the field of hypertension and cerebrovascular regulation.

Dr. Abilash Haridas is Chief of Pediatric Neurosurgery in the department of Neurosurgery at Wayne State University School of Medicine. He is a pediatric neurosurgeon specializing in cerebrovascular, skull base, endoscopic, and epilepsy surgery. After completion of medical school, he went on to post-graduate training in General Surgery at the Brooklyn Hospital Center in New York. He switched career paths to Neurosurgery and spent a year at Harvard University as he transitioned into Neurosurgery. In 2006, he joined the prestigious Mount Sinai Hospital Neurosurgery Residency program in New York City, under the direction of Dr. Kalmon Post and Dr. Joshua Bederson. Following residency he travelled to Chicago in 2011 for a Pediatric Neurosurgery Fellowship at Lurie Childrens Hospital of Northwestern University under the direction of Dr. Tadanori Tomita. In 2012 he completed an additional Cerebrovascular Fellowship at the University of Illinois in Chicago with Dr. Fady Charbel, specializing in complex cerebral bypass and aneurysm surgeries. In 2013, he joined the faculty at Wayne State University and Childrens Hospital of Michigan, bringing his rare expertise in pediatric cerebrovascular diseases.

Epilepsy, Critical Care, Oncology, Pediatric Neurosurgery, Skull Base Surgery, Vascular Neurosurgery

Dr. Moonis graduated from the Univ Coll of Med Sciences, Delhi Univ, New Delhi, Delhi, India in 1982. He works in Worcester, MA and specializes in Neurology. Dr. Moonis is affiliated with HealthAlliance Hospital Leominster and UMASS Memorial Medical Center.he has a Fellowship in Neurology of Aging and Dementia, Clinical Neurophysiology from University of Massachusetts Memorial Medical Center. Dr. Moonis is certified with American Board of Psychiatry and Neurology; Professor, Department of Neurology and Psychiatry, University of Massachusetts Memorial Medical Center; Member of the Royal College of Physicians of Ireland, (Certified), American Board of Clinical Neurophysiology I; American Board of Sleep Medicine; Director of the Acute Stroke Program and Stroke Prevention Clinic at the University of Massachusetts Memorial Medical Center, Director, Day Kimball Hospital Sleep Disorder Center; Director, Vascular Fellowship Program, UMass Medical Center; President, Board of Directors of Central Massachusetts.

Health care disparities relating to race, age and gender in stroke and dementia, optimal management and effects on primary and secondary stroke prevention, genetic markers in cryptogenic stroke to aid in sub-classification and management, clinical trials in acute stroke and stroke prevention, data mining in sleep related disorders, and stroke.

Scientist with in depth knowledge and hands on experience in stem cell biology and neurodenerative disorders such as Alzheimer's disease and Frontotemporal dementia. Always interested in potential collaborations and new career opportunities. Currently working at Copenhagen University as Associate Professor and Scientific Project Manager for Stemmad, Neurostem and Brainstem. Hands on experience with organizing research amongst different groups all over Europe in order to fulfill milestones and deliverables of several EU and local grants; including periodic and final reporting. My scientific work includes basic research using neurons derived from human induced pluripotent stem cells to develop in vitro disease models and identify novel disease mechanisms as well as overlapping pharmaceutical targets amongst neurodegenerative diseases. As a scientific project manager I am striving to streamline research and collaboration amongst our involved partners, write scientific progress reports and ensure completion of milestones and deliverables.

-Neurodegenerative Diseases - Human, mouse and porcine stem cell biology (adult, embryonic and iPS cells) - Neural differentiation and neurodegenerative disorders (Alzheimers disease, Frontotemporal dementia and Huntington's disease) - Pancreas development, specifically analysis of transcription factors in pancreatic cell lineage commitment - Human genetics with a focus on X-linked mental retardation

Dr. Ricardo is one of the world-class scientist recognized in the field of neurosciences for his unified theory of Alzheimer's disease (EA) and innovative technologies for its prevention, early diagnosis and treatment. Doctor of Science at the University of Chile, and in Biomedicine at the University of Colorado, Postdoctoral Degree at NIH and at the University of Colorado Health Sciences Center. Its successful approach has allowed to bring basic knowledge (R & D itself) to the generation of technological products. Author of relevant developments in neuroimaging, biomarkers and treatment of AD. He was Professor of Biophysics, U Colorado MedSchool and Visiting Professor at NIH, University of Gotebörg and Max Plank Institute. He has also served as Visiting Professor in several centers around the world.Dr. Maccioni is among the 5 Chilean scientists with the greatest impact in the world and has made one of the most important contributions to position Chile in the world science scene, contributing to the important public policies in the prevention of the disorders degenerative diseases of the brain.

Alzheimer’s disease (AD) and other neurodegenerative disorders

Ismail Hakki was born in 1954 in Trabzon. Elementary school Maçka completed middle and high school education in Trabzon. After completing Ataturk University Faculty of Medicine, he started as an assistant at Brain Surgery Department. After continuing his specialization at the Faculty of Medicine of Istanbul University, Department of Neurosurgery, Professor at the Neurosurgery Clinic of Zurich University. Dr. Mahmut Gazi completed his studies on micro neurosurgery beside Yasargil. He served as an Instructor at the Zurich Micro Neurosurgery Research Center, and was also involved in research in Cerebro-vascular microsurgery. He returned to Turkey at the end of 1984 and was appointed to the Presidency of the Department of Neurosurgery at Ataturk University Medical Faculty. In 1985, he first founded the University of Micro Neurosurgery Research Laboratory in Turkey. In addition to Switzerland, he has been researching at different times in Germany, France, England, Austria, Belgium, Holland, Italy, Spain, Yugoslavia, Canada, USA and Japan. In 1988, TUBITAK received the TUBITAK award in 1990 for the first time in the world to develop a new surgical technique used in the operations of brain-artery occlusions, which was literally translated in its own name. In 1991, the United States was awarded the Congress of Neurological Surgeons' INTERNATIONAL FELLOW and FCNS title for his research and contributions to surgical treatment of brain hemorrhages and aneurysms. In the same year, he was awarded by RECTORS and DECISION. AYDIN won the TURKISH NEUROSURGERY RESEARCH AWARD in 1992. The same year, he was elected to the European Stroke Science Council. In the American Stroke Council, he was given the INTERNATIONAL SCIENTIST MAN and FICA DEPARTMENT. In 1992, 1993, 1994 and 1995, he received the US Continuing Medical Education Credit Awards in Neurosurgery. In 1993, he became the first Turkish and first Muslim scientist to enter the Council by electing the Congress of Neurological Surgeons INTERNATIONAL BOARD OF DIRECTORS, as well as members of the Council of Brain Tumors, the Cerebrovascular Surgery Section and many other scientific and administrative boards in the United States. As an invited lecturer, Professor Aydin participated in many international conferences and participated in the publishing boards of scientific journals. He is the OFFICIAL LECTURER of New York Science Academy's Active, AANS 'International Member and 1994 International Skull Base Surgery Congress, was elected to the International Science Council. In 1996, the US received a Neurosurgeon Continuing Education Award with very high credit. With the cause of a research done in 1997, it was COVER to an International Neurosurgical Journal. 1999 received the Turkish Neurosurgery Award. The International Conference of the Year 2000 was selected by the United States Department of Neurosurgery (CNS). Overseas and in our country, many institutions and organizations have been appreciated and rewarded many times. In 2001 in Hidistan, due to the contributions of the Dream Science, it was transformed with CRYSTAL KÃœRE. In 2002 he was invited to Yemen, where he gave many lectures and conferences, and performed educational surgeries. In 2004, she participated in the Pakistan Brain Surgery Congress as a SURF TARGET and gave various conferences. It was abridged here with "ANNUAL AWAR 2004". At international level, more than 200 domestic and foreign scientific studies. Dr. Ismail Almighty Aydin, to this day, many Doctors, Brain Surgeons, Assist. Professor, Associate Professor and Professor. The surgical techniques developed and developed by leading scientists of the world, both abroad and in books and articles, have been included in classical books. Professor AYDIN is also present in the evaluation and decision boards of various scientific organizations besides his duty in Atatürk University Brain Surgery Department. He also works as the President of CNS 'INTERNATIONAL ASSOCIATION AND NERVOUS SYSTEM SURGERY ASSOCIATION in the USA. He is married, has three children, He speaks four foreign languages.

Cerebrovascular and Anatomical Neurosurgery

Dr. Omar is a US Board-Certified Neurologist and Neurological Oncologist. He also has subspecialized training in Endovascular Neurosurgery from the University of Oxford. Dr. Omar's main area of interest is the development of innovative approaches for the management of brain and spinal cord malignancies. He has a unique set of skills that spans across the various disciplines of Neurosciences. He received training in Endovascular Neurosurgery (University of Oxford), Neurological Oncology (University of Toronto), Neurology (University of Missouri - Columbia), Epilepsy / Epilepsy surgery evaluations, EEG, intraoperative monitoring, subdural grids and depth electrode interpretation (Cleveland Clinic Foundation) and Cellular and Molecular Neuroscience (PhD, University of Ottawa). He is a member of the Society for NeuroOncology (SNO), American Medical Association, American Physiological Society (Inactive), The Society for Neuroscience (Inactive) and the American Academy of Neurology (AAN). He is also the recipient of numerous awards including the "Medical Innovator - 2013 Award" from the Sangamon County Medical society for his discovery of a novel molecularly targeted approach for the treatment of spinal cord hemangioblastomas, Excellence Scholarship in Science and Engineering from the University of Ottawa, Prize for Outstanding Achievements from the Ottawa Hospital Foundation and a highly coveted Canadian Institutes of Health Research National Fellowship Award for investigating the role of endogenous neural stem cells in brain repair following ischemic and traumatic brain injury.

Dr. Omar's main area of interest is the development of innovative approaches for the management of brain and spinal cord malignancies.

Dr Torne is among the few super specialists who have been internationally trained in the field of Paediatric Neurology. At present Dr Torne is Head of Department of Neurosciences at Surya Children’s Hospital in Mumbai, India Dr Torne has completed her Fellowship in Paediatric Neurology and Epilepsy from Maharashtra University Health Sciences at Lokmanya Tilak Municipal Hospital and Lokmanya Tilak Municipal Medical College, Mumbai. She has had a brief stint at the University College London Hospital, a premier academic institution cum hospital in the UK. She has been trained in Paediatric Neurology at Birmingham Childrens Hospital where she successfully completed her International Fellowship in Paediatric Neurology, Epilepsy and Neurorehabilitation. To complement her advanced training in Paediatric Neurology she has completed many prestigious International courses like British Paediatric Epilepsy Training Course, British Paediatric Movement disorder Training Course in UK. She has also been trained for Ketogenic diet for drug resistant childhood epilepsies at the Asian Institute of Ketogenic Diet. Dr Torne has many accolades to her name which complements her meticulous and explicate personality. She has to her credit valuable publications in reputed peer reviewed International Journals. She has presented many national and international papers in Cambridge, Birmingham, Italy, France and Hungary. She is affiliated to many International and National Paediatric Neurology and Epilepsy associations. She was honoured by International Bursary from European Paediatric Neurology Society with an opportunity to attend one of the prestigious courses in Paediatric Neuromuscular disorder and Neonatal Neurology at Budapest in Hungary. She was invited to attend the valuable Movement Disorder International Winter School Course by Movement Disorder International society at Catania in Italy. As a feather in her cap she was invited as a Chief Guest in World Congress of Anatomist held in Gadag Institute of Medical Sciences in Karnataka.

She is a recipient of MRCPCH UK, an internationally acclaimed medical qualification. Her research interest is in complex paediatric epilepsies, ketogenic diet and paediatric movement disorder.

Prof. Harry Steinbusch is appointed as Professor in Cellular Neuroscience at Maastricht University in the Netherlands. He is President of the International Neurotoxicity Society. He is founding editor-in-chief of the Journal of Chemical Neuroanatomy, current i.f. 2.475. He is affiliated with the DGIST in Daegu, Korea; KBSI in Deagon, Korea; USP in Sao Paulo, Brazil; Tohoku University, Sendai, Japan; NIMHANS, Bangalore, India. His research interest is focussed on neurodevelopmental influences towards depression and neurodegenerative diseases studied in animal models approaches to start and prevent neurodegenerative processes. This implies combining a broad range of techniques, i.e. molecular neurobiology, quantitative neuromorphology, animal behavior and epigenetics. He has thus far guided 84 Ph.D. students. He has gathered a total of 475 papers. He has been twice coordinating a Marie Curie Early Stage Training site. Currently. He is coordinator of an Erasmus Mundus + program between 4 Euron universities and 3 universities in Japan. He is affilated on 17 editoriaal board and member of 8 International review committees. His current Hirsch factor is 69 and M-factor is 1.9.

Neurodevelopmental influences towards depression and Neurodegenerative diseases

1. Associate Director Company Name- Neurovascular Imaging Research Core, UCLA Dates Employed- May 2016 Present Employment Duration- 1 yr 6 months 2. Assistant Professor in Residence Company Name- UCLA Dates Employed- Jul 2015 Employment Duration- 2 yrs 4 months Location- Greater Los Angeles Area Department of Neurology and Computer Science 3. Visiting Assistant Professor Company Name- UCLA Dates Employed- Dec 2012 Employment Duration- 4 yrs 11 months Location- Greater Los Angeles Area

His research is directed to Stroke and traumatic brain injuries (TBI) using brain mapping of imaging and biosignals (MR, CT, X-ray angiography, TCD, and ICP).

Experienced Assistant Professor with a demonstrated history of working in the hospital & health care industry. Skilled in Emergency Medicine, Public Speaking, Neurosurgery, Healthcare Information Technology (HIT), and Grant Writing. Strong education professional graduated from Medical University/Medical Academy, Sofia.

Vascular Neurosurgery - brain hemorrhage, aneurysm, AVM, ischemic stroke

Dr. Gavin Britz earned his MBBCh at the University of the Witwatersrand School of Medicine, South Africa in 1987. He completed a surgical internship in general surgery and fellowship in general surgery at Johns Hopkins Hospital, Baltimore in 1993 and in 2002 he completed his residency in neurosurgery. During his residency he attended St. Georges Medical School, The University of London, UK and served as a Neurosurgical Registrar and Senior Registrar. After residency, he took a cerebrovascular fellowship in 2002 and an Interventional Neuroradiology Fellowship in 2003 at the University of Washington Medical School, Seattle. In 2003 he earned his MPH at the University of Washington, Seattle. He also obtained an MBA from George Washington University in 2015. He held faculty appointments at the University of Washington and Duke University before becoming a member of Houston Methodist Research Institute in 2014.

Brain aneurysm, cerebral microcirculation, acute brain injury & evaluating new and novel tools to treat a wide variety of problems such as brain aneurysms and skull base tumors

Prof. Stavros J.Baloyannis was born in Thessaloniki, Greece. He graduated from the School of Medicine of Aristotelian University of Thessaloniki, Postgraduate training (a) in Neurology in Aristotelian University and Institute of Neurology, Queen Square, London, (b) in Neuropathology in Institute of Neurology, Queen Square, Catholic University of Louvain, University of Pennsylvania, Philadelphia (c) in Neurotology and Neuropathology of Auditory pathway in Harvard University, (d). Neuropathology and Experimental Neurology, University of Pennsylvania, (e) Neuroimmunology, Yale University, New Haven. Research on Blood Brain Barrier in dementias, Blood Brain Barrier in Demyelinating diseases, Mitochondria in Alzheimers disease, Synaptogenesis in vivo and in vitro, Neuronal apoptosis in dementias and demyelinating diseases, Dendritic pathology in dementias, Pathology of Golgi apparatus in dementias. Special interests: Neuroethics, Neurolinguistics, Philosophy of Neurosciences, Application of mathematics in Neurosciences, Neurology and the Art. Member of 56 scientific societies in Greece and abroad. Honorary Member of the Academy of Hellenic Air Forces. President of the Society for the amelioration of the quality of life in chronic neurological diseases. President of the Orthodox Medical Association for support of health and medical education in Africa. He was visiting professor in Tufts University, Democretian University, Aristotelian University, School of Theology, Aristotelian University, School of Philosophy. Author of 28 textbooks on Neurology, Neuropathology, Neuropsychology and of 692 papers, published in Greek and International Journals on Neurology, Neuropathology, Neuroimmunology and Neuroethics. Head of the 1st Department of Neurology, Aristotelian University for 20 years (1992-2011). Emeritus Professor of Neurology, Aristotelian University, Thessaloniki, Greece. Director of Research Institute for Alzheimers disease and frontotemporal dementias. Archon Actuarius of the Ecumenical Patriarchate of Constantinople.

Electron Microscopy and Neuropathology of Alzheimers disease, ageing and degenerative conditions of the central nervous system

Dr. Theodore Wein MD, FRCPC, FAHA is an Assistant Professor of Neurology and Neurosurgery at McGill University where he works at the Stroke Prevention Clinic and is a William Osler Fellow. He completed his Neurology training at the Montreal Neurological Institute and went on to do his fellowship in Cerebrovascular Disease at the University of Texas – Houston. Dr. Wein is currently the co chair of the Canadian Stroke Prevention Guidelines and also sits on the Board of the Canadian Stroke Consortium where he heads the Policy and Advocacy committee focused on improving stroke care across Canada. Devoted to education Dr. Wein has chaired the annual American Heart Association International Stroke Conference pre-conference “stroke in the real world” and also sits on the steering Committee of the Canadian Stroke Congress. Dr. Wein is actively involved in stroke clinical trials and has a particular interest in stroke recovery and rehabilitation. He is lead author in the recently completed REFLEX trial looking at efficacy of botulinum toxin in treating post stroke spasticity.

Stroke, Stroke rehabilitation, Spasticity treatment and use of Botulinum Toxin

1. Director/Owner Company Name- Neuro-Psychology Practice, LLC Dates Employed- Jan 2013 – Present Employment Duration- 4 yrs 11 months Location- New York, NY 2. Assistant Professor of Neuroscience Company Name- Seton Hall University Dates Employed- Dec 2010 – Present Employment Duration- 7 yrs 3. Head of Pediatric Neuropsychology Service, JFK Medical Center Company Name- JFK Medical Center, Children's Services Dates Employed- Jan 2012 – Dec 2012 Employment Duration- 12 months Location- Edison, New Jersey 4. Staff Neuropsychologist Company Name- JFK Health Dates Employed- Sep 2007 – Jan 2012 Employment Duration- 4 yrs 5 months Location- Neuroscience Institute, Center for Head Injuries

Neurodevelopmental/neurological disorders, stroke, tumors, brain injury, epilepsy, sleep.

Dr. Altschul is a dual trained open vascular and endovascular neurosurgeon with special focus on the treatment of cerebovascular disease. David Altschul, MD—a graduate of SUNY Downstate College of Medicine in Brooklyn, New York—completed a general surgery internship, neurological surgery residency (he served as chief resident) and a fellowship in Endovascular Neurosurgery at Montefiore. He has a great interest in the open and endoscopic treatment of benign and malignant brain tumors. He is particularly interested in clinical outcomes research using new endovascular technology, as well as participating in multi-center randomized trials for the treatment of intracerebral hemorrhage, aneurysms, and AVMs. Dr. Altschul has a strong interest in resident education, currently acting as the associate residency program director. Dr. Altschul’s future research is heavily involved with potential new treatments of neurological diseases using endovascular technology. He also completed an endovascular neurosurgery fellowship at St. Luke's-Roosevelt Hospital, New York City. Dr. Altschul is one of only a few surgeons in the region trained in both endovascular (interventional) and open neurological surgery for adult and pediatric patients.

Past research has focused on the safety and efficacy of detachable micro-catheters for pediatric AVMs and the development of other minimally invasive technology for treating cerebrovascular disease. Dr. Altschul is currently involved in the ESCAPE trial evaluating endovascular stroke intervention at Montefiore.

He Studied M.B.B.S at R G Kar Medical College, Calcutta, India, Studied MCh Neurosurgery at SCTIMST, Studied Neurosurgery at National Board Certification He is working as Senior Consultant and Head of department of Neurosurgery at Al Qassimi Hospital, Sharjah Former Senior Consultant Neurosurgeon at SUT hospital pattom Former Doctor at R G Kar Medical College and Hospital Former Assistant Professor of Neurosurgery at Trivandrum Former Senior Consultant and Head of Neuroscience at SUT Hospital , Pattom Former Assistant Professor at Sree Chitra Tirunal Institute for Medical Sciences & Technology

Neurosurgery

In 1985 I graduated in Biological Science at the University of Valencia and in 1996 I finished my PhD in the IIC Institute looking for astrogliogenesis during brain development. In 1997 I spent three years at Hallamshire Hospital, Sheffield, UK. I was working in inflammation and regulation of IL-1 and IL-1 receptor. In 2000 I returned to Spain at Department of Physiology, Faculty of Medicine in University of Valencia until now. I am working in toxicity in developmental and neurodegenerative disease (such as Alzheimer’s disease) looking for oxidative stress and inflammation mechanisms

Toxicity in developmental and Neurodegenerative disease (such as Alzheimer’s disease) looking for oxidative stress and inflammation mechanisms

Dr. Pappolla's training included 3 complete medical residencies and 2 fellowships (Neurology, Clinical Pathology, Anatomic Pathology, Neuropathology, Pain Medicine), a PhD in human aging with a postdoc/sabbatical in molecular biology and over 20 years of academic practice. He holds active board certifications in these 5 areas (Neurology, Clinical Pathology, Anatomic Pathology, Neurology, Pain Medicine). Some of his research work is cited in several thousand textbooks worldwide, with many papers reaching from 300 to over 1000 citations in peer reviewed journals. His lab was among the first to identify evidence of oxidative stress in Alzheimer's disease brain. In collaborations with Dr. Larry Refolo, Dr Suzana Petanceska at the NIH, Dr. Daniel Zambon in Spain and others, we conducted groundbreaking research on hypercholesterolemia as an early risk factor for Alzheimer's disease. As a neuropathologist, he described several unique neuropathologic lesions including the colloid body of Parkinson's disease (later renamed "pale body") and the ubiquitinilated "dot like inclusions" in aged brains. One other important contribution was the development of neuroprotective drugs as potential therapeutic agents. He identified of several naturally occurring neuroprotective substances like indole-3-propionic acid and others. Dr. Pappolla served as a consultant for the National Institutes of Health in the United States including being a chartered member of numerous study sections for over 25 years and as a full professor or faculty at several medical schools (LSU New Orleans, Mount Sinai Medical School in New York City, University of Texas) where he taught Neurosciences to medical students and medical residents for over 20 years. Currently, he holds a hybrid academic-private practice position in the Houston area. Dr. Pappolla can be contacted at www.SMPSClinic.com

Alzheimer's Disease, Neuropathology, Interventional Pain Management

Dr. Michael Behen is an Assistant Professor of Pediatrics and Neurology at Wayne State University. He is a Neuropsychologist of the PET Center and manages research, teaching, and supervision of graduate students and postdocs along with neuropsychological assessments and treatment of psychiatric conditions. Dr. Behen completed his PhD in Psychology (Clinical) from Wayne State University and a fellowship in Children’s Hospital of Michigan-PET Center/Pediatrics, Neurology.

Psychology, Neurology

I completed a master degree in "cellular biology and physio-pathology" in Paris with a specialization in neurosciences, before preparing a PhD at the University of Amiens (north France). During this phD I have studied the developpement of a central nervous system cancer (C6 glioma) on a rat model, in combination to the exposure to an environmental factor (Electromagnetic fields). The analyzed parameters were behavioral, histological, and biochemical. In the future I would like to shift towards the understanding of cellular or molecular mechanisms that underlie toxicity and neurological diseases.

Neurobiology, Neurotoxicology.

Dr. Marek Czosynka is a Professor of Clinical Neurosciences Department at University of Cambridge.

Brain Autoregulation, Cerebrospinal fluid dynamics, Multi-modal brain monitoring (head trauma, poor grade SAH, stroke), Mathematical modeling of cerebrospinal dynamics, Hydrodynamic properties of hydrocephalus shunts, Software for brain monitoring

Mr. Pauls has served as President, Chief Executive Officer, and director since 2010 and was Chairman of the board from 2008 to 2014. Mr. Pauls was previously the co-founder and Managing Director of CentreStone Ventures Inc., a life sciences venture capital fund. Prior to CentreStone, he was with Centara Corporation, another early stage venture capital fund. Before this, Mr. Pauls specialized in asset-backed securitization and structured finance at the General Motors Acceptance Corporation in Minnesota. He received his Bachelor of Arts in Economics from the University of Manitoba and his M.B.A. in Finance from the University of North Dakota.

biopharmaceutics

Professor, College of Pharmacy, Ewha Womans University

Alzheimer's Disease and Dementia

Dr. Bruno Vincent, has completed his PhD from the University of Nice, France, in 1996. He then joined the Rockefeller University in New York as a post-doctoral fellow. Back to France in 1999 at the Institute of Molecular and Cellular Pharmacology in Sophia-Antipolis, he took the position of permanent researcher at the National Center for Scientific Research (CNRS) in 2001 and was promoted Research Director in 2011. In 2010, Dr. Vincent moved to Mahidol University in Bangkok where his research team is working on the identification of new AD-regulating factors. Dr. Vincent has published 60 articles in reputed international journals

Alzheimer's Disease and Dementia

A/Prof Reshma Merchant graduated from University of Edinburgh and currently a fellow of Royal College of Physician (Edin). She is currently the head of Division of Geriatric Medicine at the National University Hospital, Singapore. Her primary interest is in cognitive frailty.

Care Practice and Awareness

Bénédicte Défontaines holds an M.D. degree, advanced degrees in Biochemistry, Neurology and Neurosciences. In 2004 she create the Aloïs network, a new community-based pathway for the diagnosis and care of patients with cognitive disorders fully complementary to the existing system but more flexible and less traumatizing for patients and less costly for the State. Thanks to the creation of a consultable protocol database, the number of patients included in research protocols has risen each year. In 2014 she launched the first remote memory consultation. She plans to expand this approach to French people living abroad. She is an Ashoka Fellow.

Neurology, Alzheimer's Disease

Institute of Biomedical Sciences, Academia

Neurology, Alzheimer's Disease and Dementia, neuroprotection mechanisms against Alzheimer’s disease

Herman Moreno: Associate Professor of Neurology and Pharmacology/Physiology at SUNY Downstate, New York USA: The laboratory of Moreno focuses mainly in functional analysis of mice modeling Alzheimer’s disease and other neurodegenerative diseases. The team uses, state of the art electrophysiological techniques, coupled with calcium imaging and functional MRI

Alzheimer's Disease and Dementia

Nela Pivac is senior scientist, re-elected, at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, and Associate Professor at the Interdisciplinary PhD study in Osijek University. She is Associated Editor of Progress in Neuro-Psychopharmacology and Biological Psychiatry, head of the Laboratory for Molecular Neuropsychiatry, main editor of the RBI Annual report, and leader of numerous national and inernational projects. She has won 4 State Awards for scientific achievements and published 139 scientific papers and 38 chapters in the books, cited 2948 times, H-index=32; and serves as reviewer for domestic and international projects and numerous reputed journals.

Alzheimers disease and Dementia

Dr. Ian James Martins is an Editor/Reveiwer for Open Acess Pub/MDPI journals. Appointed as the Chief Editor for International Journal of Diabetes Research (2014-2018), Research and Reviews: Neuroscience (2016-2018) and Journal of Diabetes and Clinical Studies (2017-2018). BIT Member (BIT Congress. Inc). Scientist for Science Advisory Board (USA) and Academic with Academia.edu. H-index of 43, (ResearchGate STATs (23), Mendeley STATS (20). Scientific research citations accumulated to >3300. Lifetime Membership by International Agency for Standards and Ratings as Fellow. Winner (World Academic Championship -2017) in Diabetes and Medical Science (Nutrition). Conferred with the RICHARD KUHN RESEARCH AWARD-2015 ENDOCRINOLOGY AND METABOLISM

Alzheimer's Disease and Dementia

Claude M Wischik holds the Chair in Old Age Psychiatry at the University of Aberdeen in Scotland, and is Executive Chairman of TauRx Pharmaceuticals. He studied medicine in Australia, completed his PhD at the Laboratory of Molecular Biology in Cambridge, and also higher psychiatric training in Cambridge. He was the first to identify Tau protein as the main constituent of the Alzheimer tangle and developed the first Tau Aggregation Inhibitors. He has published 121 papers and holds 11 patent groups based on his work with over 40 individual patents.

Alzheimer’s disease, frontotemporal dementia

Dr. A.V. Srinivasan is the President of Indian Academy of Neurology and also he is the emeritus Professor of The Tamilnadu DR.M.G.R.Medical University. • Dr A V Srinivasan, driven by his quest for excellence and the latest discoveries on human brain related disorders, joined Madras Medical College (MMC) and received MD(General Medicine) in 1978.Later he pursued and received DM in Neurology from his alma mater.He is First Neuro physician of his state Tamil Nadu in India in government service to be conferred, the Fellow of the Royal College of Physicians (FRCP) in London in 2012, fellowship of the Indian Academy of Neurology 2004 and fellowship by the American Academy of Neurology, in 2003.He Is the First Indian to receive American Indian Neurology Award (AINA) in USA in 2001, for the best paper presentation IN STROKE during annual American Academy of Neurology meeting in 2001 in PHILADELPHIA. ByTheTamil Nadu DR. MGR Medical University. Currently serving as a Member –in the ACADEMIC COUNCIL of National institute of Mental health and Neurosciences, Deemed University, Bangalore.

Neurology

Dr. Rajendra D. Badgaiyan, MD, is a psychiatrist and cognitive neuroscientist. He is Chairman of the Department of Psychiatry and Behavioral Sciences at Richmond University Medical Center, and Professor of Psychiatry at Icahn School of Medicine at Mount Sinai in New York. He received formal training in psychiatry, psychology, cognitive neuroscience, molecular imaging and neuroimaging. He was awarded the prestigious BK Anand National Research Prize in India and Solomon Award of Harvard Medical School. His research is focused on the study of neural and neurochemical mechanisms that control human brain functions. He developed the single scan dynamic molecular imaging technique (SDMIT) to detect, map, and measure neurotransmitters released acutely in the human brain during task performance. This technique is now used in laboratories all over the world. Using this technique, he studies dopaminergic control of human cognition and behavior. He is also interested in learning the nature of dysregulated dopamine neurotransmission in psychiatric and neuropsychiatric conditions. His research is funded by NIMH, NINDS, VA, and various foundations. Previously he served in the faculty of Harvard Medical School, SUNY Buffalo and University of Minnesota. He has published extensively in peer-reviewed journals.

Psychiatry, Cognitive Neuroscience

John M Baumann inspires and helps real people to live their lives to the fullest, and even embrace their life-changing event, with the goal of uncovering their life’s purpose. He is an internationally-recognized inspiring success speaker. In 2002, working as the top attorney for a public company, he was diagnosed with Parkinson’s disease. From 2005 until 2014, he taught law at the College of Business at the University of Louisville to over 1,000 undergraduates. He was selected the Most Inspiring Professor. He wrote a book entitled, “Decide Success - You Dead Yet”. He earned his Juris Doctorate degree from Cornell Law School after graduating Summa Cum Laude with a Bachelor’s Degree in Business Administration from the University of Massachusetts, School of Management. As an attorney, he has passed the bar and practiced law in Texas, Louisiana and New Jersey before becoming General Counsel of a NASDAQ listed corporation headquartered in Kentucky.

Parkinson disease

Dr. Ben Weinstock has over 30 years of experience in the rehabilitation of patients suffering from complex medical and neurological conditions. He has presented previously at international conferences. In 2015 he wrote and published the only book about the prevention of PD. In 2017 he began to present his course, Exercise Prescription, Individualized Care for PD (EPIC-PD™) to Doctors of Physical Therapy. EPIC-PD is the only methodology that takes motor and non-motor factors into account to develop an individualized exercise and lifestyle prescription for a person with PD.

Disease prevention Geriatrics Neurological rehabilitation, especially Parkinson's Disease Autonomic dysfunction

• Dr Attarian is currently a professor of neurology and medical director of sleep medicine and sleep fellowship at Northwestern University. He graduated with a MD in 1992 from American University of Beirut and completed residency in Neurology at Upstate Medical University in Syracuse and fellowships in epilepsy and sleep medicine at University of Rochester and Hennepin County Medical Center respectively. He has Published 70 peer reviewed papers, 20 chapters and three textbooks. He has lectured nationally and internationally including Shanghai China and Moscow Russia and participated in 30 research projects and got three grants. He has won teaching awards.

Hrayr Attarian primary research interests are in sleep disorders in women and the treatment of parasomnias,Epilepsy.

Joseph I. Sirven, M.D., is a professor of neurology and editor-in-chief of Epilepsy.com. He is currently chair of the AAN Education Meeting Subcommittee and he is on the board of directors for the American Brain Foundation and the editorial board of Neurology Now. Previously, he served as director of education for Mayo Clinic's Arizona campus with oversight over all educational activities at the Arizona campus, including medical student rotations, residencies, fellowships, Ph.D. candidates, nursing, allied health and continuing medical education programs. He was the previous chair of Neurology at Mayo Clinic's campus is Arizona and the previous vice chair of the Epilepsy Section of the American Academy of Neurology, chair of the Communication Council for the American Epilepsy Society and former chair of the Professional Advisory Board for the Epilepsy Foundation.

Epilepsy and seizure treatments in adults and children (particularly older adults) Epilepsy surgery Electroencephalography Investigational anti-epilepsy drugs Status epilepticus Vagal nerve stimulator Ketogenic diet

Dr. Alain L. Fymat is a medical-physical scientist and an educator who was educated at the Universities of Bordeaux and Paris-Sorbonne, France, and the University of California at Los Angeles. He is the current President/CEO and Professor at the International Institute of Medicine & Science. He was formerly Professor of Radiology, Radiological Sciences, Radiation Medicine (Oncology), Critical Care Medicine, and Physics at several U.S. and European Universities. His current research interests lie at the interface between science and medicine (neurological disorders; precision medicine; nanobiotechnology; nanomedicine; genetics/epigenetics/ecogenetics; and drug delivery across the brain protective barriers). He has extensively published (~350 scholarly publications) and lectured in several national and international academic, professional, governmental and industrial venues. He is a a Board member of several institutions, and Editor-in-Chief, Honorable Editor or Editor of twelve scientific Journals.

Radiology, Medicine

Antonio Gambardella is full professor of Neurology in the Department of Medical and Surgical Sciences, University Magna Graecia - Catanzaro, Italy. He is a clinical neurologist and clinical researcher with a special interest in establishing close research links with basic scientists. His group, together with molecular genetic collaborators in Italy, discovered in 2000 the beta2 nicotinic acetylcholine receptor gene for nocturnal frontal lobe epilepsy and subsequently has been involved in the discovery of other epilepsy genes. A more recent important scientific result has been the discovery of novel gene KCNT1 associated with a severe form of progressive myoclonus epilepsy. He has also focused on clinical and neurophysiological aspects, and genetics of temporal lobe epilepsy, the most common type of focal epilepsy. He is currently an active investigator of the "Epi25" Collaborative group that has developed from an initiative coming out of the NIH National Human Genome Research Institute (NHGRI) and the International League Against Epilepsy (ILAE) Consortium on Genetics of Complex Epilepsies to make more rapid progress towards fully understanding the inherited components of epilepsies

Epilepsy, Neurology

Natalia Rodríguez Álvarez is the Postdoctoral research Scientist in the department of Physiology and Medical Physics in the Epilepsy Research Group at the Royal College of Surgeons in Ireland. Combining the principles of molecular biology and neurobiology, electroencephalography, pharmacology and genetics at both undergraduate and postgraduate level has led to a broad knowledge base in a multidisciplinary field with additional experience in drug discovery and biomarkers.

Epilepsy,Medicine

Dr. K. S. Ravi holds M.D. Anatomy degree from India’s most prestigious Institute, JIPMER Pondicherry.He has worked as an Assistant Professor in Sri Venkateshwara Medical College Hospital & Research Centre in Pondicherry & Sri Muthukumaran Medical College Hospital & Research Institute, Chennai. Before Joining AIIMS Rishikesh on 18th August 2012 as faculty of Anatomy, Dr. Ravi was working as Assistant Professor and Course Director & Head of Anatomy at School of Medicine, Spartan Health Sciences University, St. Lucia, North America. Dr.Ravi has been Assistant Dean(Academics) and presently working as Sub-Dean(Academics),AIIMS Rishikesh.Apart from his contributions to the field of medicine, Dr. Ravi is also a creative writer. He was awarded the “Best Creative Writer” in 1997 for one of his stories. His articles have been published in various magazines and leading national newspapers of India, including- The Times of India, The Pioneer and The Hindustan times. He has furthered his literary interests by serving on the editorial boards and reviewers of several National – International Journals and magazines

Neuroanatomy,Medicine,Health Sciences

Dr.Ameen Al-KAMALI is professor of Neurosurgery at Ain Shams University. Faculty of medicine at Sana'a University

Neurology, Neurosurgery,Child and Adolescent Neurology

Roberto Alexandre Dezena M.D. is from Federal University of Triângulo Mineiro, Uberaba, Brazil (2003), medical residency in Neurosurgery at Santa Casa de Misericórdia de Ribeirão Preto, Brazil (2009), Ph.D. in Neurosurgery at Ribeirão Preto Medical School of University of São Paulo, Brazil (2011), and Postdoctoral Fellowship at Federal University of Triângulo Mineiro, Uberaba, Brazil (2014). Fellow of Eberhard-Karls Universität Tübingen, Germany, Hiroshima University, Japan, and Saint Louis University, USA. In Brazil, he is Full Member of Brazilian Society of Neurosurgery (SBN) and Brazilian Academy of Neurosurgery (ABNc), besides vice president of Minas Gerais Neurosurgery Society and member of deliberative counsil of Brazilian Academy of Neurosurgery. Internationally, he is Fellow of World Federation of Neurosurgical Societes (WFNS), Active Member of International Federation of Neuroendoscopy (IFNE), Active Member of International Society for Pediatric Neurosurgery (ISPN), Active Member of Walter E. Dandy Neurosurgical Society (WEDNS), and Full Member of both Latin American Federation of Neurosurgery Societes (FLANC) and Latin American Group of Studies in Neuroendoscopy (GLEN). Currently is Associate Professor and Chief of Division of Neurosurgery, Clinics Hospital, Director of Neurosurgery Residency Program and Professor of Postgraduate Program in Health Sciences and Postgraduate Program in Applied Biosciences, all at Federal University of Triângulo Mineiro, Uberaba, Brazil. Director of the Reference Center for Continuing Education of Latin American Federation of Neurosurgery Societes (FLANC), at the same university. Neurosurgical activities in Microneurosurgery (vascular and neuro-oncology), Endoscopic Neurosurgery, Pediatric Neurosurgery, Spine Surgery and Neurotrauma. Furthermore is editorial board member and reviewer of several international scientific journals, highlighting World Neurosurgery (WFNS), Neurological Research (Maney) and Journal of Neurosurgical Sciences (Minerva).

Neurology,Neurosurgery , Pediatric Neurosurgery, Endoscopic Neurosurgery,Neurotrauma, Spine Surgery

Riaz Ahmed Competent and well trained neurologist with 2 European certifications and Fellowship: Fellow of Royal College of Paediatrics and Child Health, UK as well Fellow of Royal College of Physicians of Ireland - Comfortable with all aspects of neurology, including Epilepsy management In Paediatrics and neurophysiology (electroencephalography and electromyography). Has more than 40 publications in Peer viewed Neurology Journals - Editorial board member in 3 International Neurology Journals. - Member of International Child Neurology Association, Asian Oceanean Child Neurology Association, Indian Neurological Society, Infantile |Seizure Society & American Academy of Neurology.He is currently working as Consultant & Head of Paediatric Neurology at KFAFH

Epilepsy management In Paediatrics and neurophysiology (electroencephalography and electromyography).

Dr. Dan Suiaga With a rich experience in all types of neurosurgical interventions, Dr. Dan Suiaga is recognized for interventions in complex spinal surgery (implants and spinal reconstruction, etc.), but also for cerebral vascular surgery or skull base. Although he started his professional training at the neurosurgery department of the University Hospital in Cluj-Napoca, Dr. Dan Suiaga continued to train outside the borders of Romania, in countries such as Switzerland, Israel, Germany and South Africa.

Clinical Science

Dr. Francisco Javier Ruiz Miyares is a Neurologist with a varied range of interests within clinical neurology, mainly epilepsy of childhood onset. Diverse aspects from teaching to research within a clinical praxis framework, encompass his goals including semiology-semiothecnia, neurophysiology, epidemiology with an exchange platform as a congress organizer, being the former Neurology Conferences, now NeuroSantiago events, a successful pathway of interaction amongst many neuroscientists from diverse part of the world. Master of Sciences in Infectology, Assistant Professor and Second Degree Specialist and Researcher, was CME coordinator of the World Federation of Neurology in the eastern part of the island more than 10 years

Neurology,Epilepsy,Neuroscience,Pediatric Neurology,Neurophysiology and Epidemiology

Intractable seizures plague approximately a third of epilepsy patients. Despite their prevalence, the mechanisms underlying intractable seizures remain unclear and difficult to study. One factor clouding our understanding of seizure intractability stems from existing animal models of epilepsy, which have not specifically modeled intractable seizures or genetic disorders that often associate with intractable seizures, like Focal Cortical Dysplasia (FCD) or Tuberous Sclerosis Complex (TSC). New animal models are greatly needed to understand the underlying causes of intractable seizures and develop new therapies aimed at these indications. Using in utero electroporation to transfect a small population of neurons in vivo with constitutively active mutant of Ras homolog enriched in brain (RhebCA), we have successfully developed a new mouse model of spontaneous epilepsy based on the genetic etiology of mTOR-o-pathies. This model recapitulates both anatomical and behavioral phenotypes of human TSC and FCD. RhebCA transfected animals develop focal cortical malformations that contain dysplastic neurons, cortical dyslamination and white matter heterotopia. Seizures also spontaneously develop as early as postnatal day18, and persist throughout entire lifespan of the animals (2 years). Seizures are the only complication these animals have, otherwise they are completely healthy, making them ideal subjects to study mechanistic causes of seizures and seizure-dependent downstream behavioral and physiological effects. With this model, we have elucidated several mechanisms that contribute to seizure-genesis in TSC and FCD. Lastly, we also use this model to develop new therapies, including novel cannabinoids and RNA interference approaches to mitigate refractory seizures

Neuroscience , Neurosurgery

Dr.Omar García is currently a Professor from university Anáhuac with the Department of Neurology.He is the Neurosurgeon at Mexican Society of Neurological Surgery. Dr.Omar done his education from National Autonomous University of Mexico. He is also invited Professor at Pre and postgraduate courses. He is the member of Neuro trauma section

Neurosurgery,Tumors, Skull base, Derivation systems,Vascular surgery,CNS infections Spine surgery,Congenital disease,Degenerative disease,Tumors Fixation and instrumentation Trauma

Dr. E. Faizo. is a certified licensed Medical Doctor specialized in Neurosurgery and spine surgery practicing in Murnau Hospital south Germany. He presented in international seminars, media interviews and conferences in Health Care and education. Member of the Advisory boards in many German medical companies. Member of the German and European Neurosurgical Societies.

Spine surgery in research and pain therapy , Neuromodulation

Dr. Nino Devidze is the Director of Neuroscience Research, Gene Therapy Program in Perelman School of Medicine of University of Pennsylvania. She was the Principal Scientist at Bristol-Myers Squibb. And also she served as a Director of Neurobehavioral Core Laboratory at Gladstone Institute of Neurological Disease, San Francisco. She has received many awards and she published over 51 scientific abstracts.

Neuroscience, Gene Therapyand her current focus is developing AAV therapies for Neurodevelopmental Diseases

Dr. Alberto E. Musto, MD, PhD, FAES, is an Assistant Professor of Pathology and Anatomy, one of the Module Directors of the Pre-clerkship CareForward Curriculum, School of Medicine and Director of Neuroanatomy course, School of Health Professionals at Eastern Virginia Medical School in Norfolk, Virginia. Dr. Musto integrates an interdisciplinary approach in medical education and mentorship activities in neuroscience research to enhance research, and diversity in the new medical curricula. He has been bestowed with a prestigious award -- Fellow of the American Epilepsy Society (FAES) – a lifetime professional honor in recognition of his accomplishments and dedication to excellence in epilepsy. He has several publications in major journals in the field of neuroscience and epilepsy, including with his colleagues patents in neuroprotection and against glioblastoma multiforme development. He has been a member of NIH grant review study sections.

Interests: His primary research interest is to understand the immune-inflammatory process in the neural tissue following a brain injury that contribute to aberrant neuronal networks formations which mediate the development of epilepsy.

Jeffrey David Lewine, PhD is a Professor of Translational Neuroscience, and the Director of Business Development at the MIND Research Network in Albuquerque, New Mexico. He is also the Director of Neuroscience for Lovelace Scientific Resources; an adjunct associate professor in the departments of Psychology and Neurology at the University of New Mexico; the Director of Clinical Research for Cognionics Inc.; and the CEO of the Center for Advanced Diagnostics, Evaluation, and Therapeutics. Dr. Lewine received his doctorate in neuroscience in 1989 from the University of Rochester. Following completion of his graduate training, he was named a Director's Fellow at Los Alamos National Laboratory where he worked on the development of advanced brain imaging technologies. Dr. Lewine has previously directed functional brain imaging programs in New Mexico, Utah, Kansas, and Illinois, and his research uses advanced behavioral, psychophysical, imaging (MRI, fMRI, DTI, SPECT), and electrophysiological (EEG, MEG) methods to study brain structure and function in health and disease. Dr. Lewine evaluates human subjects and animal models to explore a wide range of clinical conditions including autism, dementia, epilepsy, reading disorders, schizophrenia, PTSD, and traumatic brain injury. These investigations include the development and evaluation of novel therapies and biomedical countermeasures, and they have been funded by the National Science Foundation, the National Institutes of Health, the Department of Energy, the Department of Defense, and the Biomedical Advanced Research and Development Authority. Dr. Lewine has directed functional brain imaging programs in New Mexico, Utah, Kansas and Illinois, and is the co-author of more than 100 peer-reviewed research articles and book chapters.

Autism, Traumatic Brain Injury, Post-Traumatic Stress Disorder, Tinnitus, Epilepsy, Neuro-Plasticity

Walter Bini has completed his diploma from Westminster School, Simsbury Conn. U.S.A. and got postgraduate degree from Universidad de Zaragoza , Facultad de Medicina, Zaragoza-Spain. Presently since 2014, Middle East Chairman of ISLASS. Active Member and Board Member of numerous international societies , among these : SAS, German Neurosurgical Society, AANS and the Skull Base Study Group. He was Head of Neurosurgery, Sheikh Khalifa General Hospital , UAQ-UAE from 2014-2016. Currently he is Consultant Neurosurgeon, Orthopedic Department, spine section of Lanzo Hospital COF, Lanzo d’Intelvi in Italy and also Visiting Consultant Neurosurgeon, Orthopedic Department of Healthpoint Hospital in Abu Dhabi - UAE

Micro neurosurgery, special interest and expertise in the management of head trauma, neurooncology, stereotaxy and radiosurgery, spinal surgery including less invasive techniques and neuroradiology

Dr. Miguel Angel Maroto Serrano is a Psychologist, Clinical and social Gerontology Expert in Active and Dementia Aging. He is the Coordinator and Professor of University Postgraduates Technical and Director of professional teams. He is the author of technical manuals on elderly people and dementias (8 works published by the Community of Madrid and Tea Editions)and Director and Manager at Clinical and Social Intervention Center and Ahoracentros

Psychology, Gerontology, Alzheimer's and Dementia

Lynne Hughes is vice president and global head of QuintilesIMS’ Neurology Center of Excellence (CoE), where she develops evidence-based strategies to conduct clinical programs for customers. She also leads the Autism CoE and the Acute Care and Pain CoE. Dr. Hughes has worked in the industry for more than 30 years, including 20 years at QuintilesIMS, and has worked both in Europe and the US. Lynne has worked exclusively in neurology while at QuintilesIMS and possesses expertise in all areas on Neurology, including Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, epilepsy, acute care and pain. Dr. Hughes has been involved in the clinical trial development of many of the neurological therapies on the market today. She is a member of a number of steering and executive committees for clients and has responsibility for several consultancy programs for investment opportunities within all areas of neurology. Dr. Hughes earned her bachelor’s degree in Medical Sciences from the University of Bradford in Bradford, England. She completed her Ph.D. in Oncology and Cancer Biology at the University of Birmingham, in Birmingham, England, fully sponsored by Cancer Research UK. In addition, she is certified as a Project Management Professional.

Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis, Neuro-orphan diseases.

Dr. Drini DOBI was born in January 27th, 1969, and graduated as PhD in University of Tirana, Albania in 1992, and has done the specialization course in Neurology from 1994-1998 in University Hospital Centre "Mother Teresa", Tirana Albania. After his specialization, he has done some other minispecialization course for neurorehabilitation in Instituto Carlo Besta, Milano, Italy, San Carlo , Milan, Italy and Don Carlo Gnocchi Milano, Italy and minispecialization course for neurosonology in UHC "Sestre Milosrdnice" Zagreb, Croatia. He has a lot of publications in some medical periodics and has participated in some of AAN Annual Meetings with his works, EFNS and EAN conferences, with his works too, and some other Neurological Conferences abroad. His Masters is in Rehabilitation in Parkinson Disease, in 2005 and PhD in Physical Rehabilitation after stroke in 2015. He is also the Member of EAN Scientific Pannel of Neurorehabilitation ,Scientific Pannel of neurotoxicology, and General Neurology

Neurorehabilitation and Stroke

Pant received his M.A. and Ph.D. degrees in Physics from Agra University, Agra, India. His postdoctoral studies were conducted on the mechanisms of electron and ion transport in model membrane systems at the Department of Biophysics at Michigan State University. He joined the Laboratory of Neurobiology in the NIMH as a senior staff fellow in 1974 with Dr. Ichiji Tasaki where he studied the function of the axonal cytoskeleton in the squid giant axon. In 1979 he moved to the NIAAA extending his studies on the neuronal cytoskeleton and the effects of alcohol on its regulation. Dr. Pant moved to the NINDS, Laboratory of Neurochemistry in 1987 where he is presently chief of the section on Cytoskeleton Regulation. His laboratory is studying the mechanisms of topographic regulation of neuronal cytoskeleton proteins by post-translational modification, including the role of kinase cascades in normal brain and during neurodegeneration.

Parkinsion’s and Alzheimer’s Diseases

Ateeq Ahmad, Ph.D. is vice president for science & technology at Jina pharmaceuticals, Inc., USA. Prior to joining Jina in 2006, Dr. Ahmad worked at Neopharm, Inc., Pharmacia (Searle), Sanofi, J &J, Medarex, Biotherapeutics and National Institutes of Health. He has more than 30 years of experience in drug discovery, drug targeting, therapeutic proteins, immunotoxins, liposomes and clinical pharmacology. Currently, Dr. Ahmad is directing drug development program including safety assessment, efficacy evaluation and pharmacokinetics of drug candidates for cancer therapeutics and neurological disorders. He has authored 61 original articles in peer reviewed scientific journals.

Drug discovery, drug targeting, therapeutic proteins, immunotoxins, liposomes and clinical pharmacology

Sanjoy Sanyal is Associate Dean, Clinical Neuroscience Professor, Surgeon and Informatician in Texila American University, Guyana, South America. He holds double Master's degrees from India and UK. He has published more than 50 papers in print and online journals. He is a Neuroscience editor and peer-reviewer of WebmedCentral. He has posted more than 300 Neuroscience videos online, accompanied by his running commentaries. He is currently writing a Neuroscience book for medical students. He has presented papers in more than 10 international forums. He holds a provisional patent from USPTO on a computerized program for staging 26 human cancers.

Schizophrenia and Bipolar disorder

In 1993 Kerensa started her study nutrition and dietetics in Amsterdam. After finishing the bachelor in 1997, she continued with a master degree nutrition and food management at Huddersfield University in the UK. From 2000 until 2005 she worked as a PhD student at Wageningen University on the biophysics of unfolding, refolding and aggregation of food related proteins. Her first postdoctoral work was at the Medical Research Council – Laboratory of Molecular Biology in the Neurobiology department in Cambridge, UK. This work focused on fatty acid – a-synuclein interactions employing both biophysics and cell culture as research tools. Her second postdoc was at the Free University of Brussels (VUB) in Belgium where she started working on the role of amyloid beta peptide in Alzheimer’s disease. Here she also obtained an Odysseus grant from the Belgian government and, as a result of that, was offered a position as assistant professor. Kerensa moved to her current position as an assistant professor at the University of Twente in March 2011. She prefers to spend her spare time in the dojo doing karate, travelling, gardening or reading.

Alzheimer’s, Parkinson’s disease, prion diseases

Dr. Hernández, Ph.D. has been studying traumatic brain injury (TBI) using basic and clinical neuroscience models since 1985. Her ongoing, extramurally funded research program assesses the degree to which recovery and functional outcome after TBI can be optimized in a variety of populations (Veterans, civilians, athletes). This includes conducting randomized, placebo-controlled, blinded trials of novel interventions, such as acupressure. This work is accomplished through her appointment as Professor and Chair of the Department of Psychology & Neuroscience at CU Boulder, her appointment as a Senior Investigator and Research Psychologist in the Eastern Colorado Healthcare System, Rocky Mountain MIRECC (Mental Illness, Research, Education & Clinical Center) and through her role as one of the co-Directors of the PAPRR (Promoting Athlete Performance, Recovery and Resilience) Board at CU Boulder. She is also the Director of the CAIRR (Clinical Assessment of Injury, Recovery and Resilience) Neuroscience Laboratory.

Research is aimed at providing an experimental basis for improving clinical treatment following brain insult so that neurobehavioral function is optimized. We are currently accomplishing this via two tracks: one aimed at the initial post-injury period and a second focusing on the stable post-insult period

Dean Faculty of Pain Medicine 2015 – 2018. Consultant and Medical Director Pain Medicine, St. James’ Hospital, Dublin. Primary Investigator, Trinity College Institute of Neuroscience. Senior Lecturer, School of Medicine, Trinity College, Dublin. Editor: BJA; Continuing Medical Education. Pain Clinic, Blackrock Clinic 2004 – date. Graduated RCSI 1988. Trained in Ireland, UK and Karolinska Institute, Stockholm and Lund University Hospital, Sweden.

Spinal Neuronal,Chronic Pain, Cancer Pain

Hans von Holst received his Medical Doctor´s degree in 1976 and specialist in Neurosurgery 1982 at Karolinska University Hospital. In 1985 he earned his PhD and Associate Professorship in Neurosurgery, Clinical Neuroscience at Karolinska Institutet. During 1991-1996 he was appointed as Chairman of the Dept of Neurosurgery and Division Manager of the Neuroclinics at Karolinska University Hospital, respectively. In 1995 he became Professor in Neuroengineering at the Royal Institute of Technology. He has published around 140 original papers in reputed journals, reviews and books and has been serving as an editorial board member in several journals.

traumatic brain injury and stroke

Ru-Rong Ji, Ph.D., is a professor of anesthesiology. He also serves as chief of pain research in the Department of Anesthesiology. He previously was an associate professor at Brigham and Women’s Hospital, Harvard Medical School, before joining the Duke faculty in 2012. His research focuses on molecular and cellular mechanisms of chronic pain, such as inflammatory pain, neuropathic pain, and cancer pain. He is internationally recognized for his contributions to demonstrating critical roles of MAP kinase signaling pathways and glial cells in the pathogenesis of chronic pain. His recent work has demonstrated powerful antinociceptive actions of pro-resolution lipid mediators (e.g., resolvins). Dr. Ji lectures internationally and reviews papers for numerous international journals. He also serves on National Institutes of Health review panels and the editorial boards of Pain, Neuroscience, and Neuroscience Bulletin. Dr. Ji earned a Ph.D. in neurobiology at Shanghai Institute of Physiology and completed postdoctoral training at Peking (Beijing) University Medical School, Karolinska Institute, and Johns Hopkins University School of Medicine. He later joined Massachusetts General Hospital as an instructor.

Inflammatory pain, neuropathic pain, and cancer pain

After his BSc Honours and an MSc in theoretical mathematics, Professor Toro obtained a PhD in computational mathematics applied to fluid dynamics. Since then, much of his research has been centred on the numerical analysis of partial differential equations and aerospace, industrial, environmental and medical applications. He is author of almost 300 works and has received several awards, including two honorary doctorates and the honorary title OBE from her majesty The Queen Elizabeth II. Prof. Toro’s current research is focused on the bio-physics of neurological diseases and their potential link to venous haemodynamics and transport across the blood vessel wall

Neurodegenerative diseases

Mark S. Kindy, Ph.D. is Professor of Neurosciences at the Medical University of South Carolina, Adjunct Professor of Bioengineering at Clemson University, Adjunct Professor of Chemical Engineering at the University of South Carolina, Adjunct Professor of Management and Entreprenurialism, School of Business, College of Charleston. He received his BA in zoology from the University of Massachusetts in 1980. Dr. Kindy received his Ph.D. in Biochemistry from Boston University School of Medicine from 1982-1987. He was a post-doctoral fellow at the Salk Institute from 1987-1989 in Molecular Biology and Virology. From 1989-2002, Dr. Kindy was a faculty member in the Department of Biochemistry at the University of Kentucky and rose from Assistant Professor to Full Professor. Dr. Kindy is currently the Admiral Pihl Endowed Professor in the Department of Neurosciences. Dr. Kindy is also a Research Career Scientist at the Ralph H. Johnson VA Medical Center in Charleston. Dr. Kindy has served on many NIH, AHA, AA review panels, has reviewed for many journals and is currently on the editorial board of 10 journals. Dr. Kindy has over 140 peer reviewed publications and is funded by the NIH, VA , NSF and several foundations.

Neurological disorders

Dr. Hernández, Ph.D. has been studying traumatic brain injury (TBI) using basic and clinical neuroscience models since 1985. Her ongoing, extramurally funded research program assesses the degree to which recovery and functional outcome after TBI can be optimized in a variety of populations (Veterans, civilians, athletes). This includes conducting randomized, placebo-controlled, blinded trials of novel interventions, such as acupressure. This work is accomplished through her appointment as Professor and Chair of the Department of Psychology & Neuroscience at CU Boulder, her appointment as a Senior Investigator and Research Psychologist in the Eastern Colorado Healthcare System, Rocky Mountain MIRECC (Mental Illness, Research, Education & Clinical Center) and through her role as one of the co-Directors of the PAPRR (Promoting Athlete Performance, Recovery and Resilience) Board at CU Boulder. She is also the Director of the CAIRR (Clinical Assessment of Injury, Recovery and Resilience) Neuroscience Laboratory.

ur clinically-based program of research is aimed at providing an experimental basis for improving clinical treatment following brain insult so that neurobehavioral function is optimized. We are currently accomplishing this via two tracks: one aimed at the initial post-injury period and a second focusing on the stable post-insult period.

Chris Gamblin completed his PhD with Dr. Robley Williams, Jr. at Vanderbilt University and postdoctoral studies with Dr. Skip Binder at Northwestern University Feinberg School of Medicine. He is currently an Associate Professor in the Department of Molecular Biosciences at the University of Kansas and continues to investigate the biochemical mechanisms of tau aggregation.

Dr Davide V Moretti is consultant neurologist, chief of the clinical neurophysiology service and researcher at the National Institute of Research and Cure for Mental disorders and Dementia S john of God, Brescia, Italy. He received his medical degree from Catholic University in Rome and completed his residency in neurology and fellowship in movement disorders at University of Trieste, Italy. Moreover, he received the PhD in neurophysiology at La Sapienza University (thesis title “ Quantitative EEG in Alzheimer's disease”). Dr Moretti is currently involved in research and care of subjects with Alzheimers disease and dementia in the Memory Clinic/Alzheimer Operative Unit of the S. John of God Institute. Moreover, he is the chief of the clinical neurophysiology unit. His research is primary concerned about quantitative EEG evaluation of Alzheimer's patients both in prodromic and clinically evident phase of the disease.

Alzheimers disease and dementia

Dr Wayne Grant Carter received his Honours degree and PhD in Biochemistry from the University of Southampton, studying protein post-translational modification and molecular signalling cascades. He is currently a Group Leader in the School of Medicine, University of Nottingham, with research focused upon protein post-translational modification and molecular mechanisms of hepato- and neuro-toxicity.

Rocco de Filippis completed his MD and PhD from Catholic University of the Sacred Heart in Rome. Investigator Meeting (Western Europe and North America) for BRENDA/pharmacological Study on Nalmefene (LUNDBECK - pharmaceutical company). Barcellona (Spagna) . He holds a Master’s degree and he improved respectively in Bipolar Disorders and Addictive behavior in the years 2011/2012. He currently works and at the Institute of Psychopathology - Rome as a Psychiatrist and Addictive Medicine, and up to now presented as scientific coordinator of CME and Master of Addictive Behaviors; he currently publishes on Bipolar Disorders with high specialization on rapid cycling;he is also an official candidate at the Psychoanalytic Italian Society of the First Italian Center of Rome, and member of IPSO (International Psychoanalytic Studies Organization). He had a oral speech at Translational Medicine 2014 in Las Vegas on QTc Prolungation and Psychotropic Drugs.

AJA Groffen has completed his PhD at the age of 29 years from the University Medical Center in Nijmegen, The Netherlands and performed postdoctoral studies at the University Medical Center Utrecht, The Netherlands. He was appointed Assistant Professor at the dept. of Clinical Genetics (section Functional Genomics) at the VU University Medical Center in Amsterdam, The Netherlands. He has published more than 25 papers in reputed journals.

movement disorders, epilepsies, cognitive and autism-related disorders

HND qualification at Cambridge Polytechnical College, Cambridge, UK (1971), Honour’s degree (Psychology and Physiology) at Newcastle-upon-Tyne University (1974), and PhD, Uppsala University, Uppsala, Sweden (1979), Astra Läkemedel AB ( Head of CNS Drugs), Professor and Chair of Biological Psychology, Head of Department and Dean of Faculty, Visiting Professor at: University of Hawaii at Manoa, Örebro University, Karlstad University, Kalmar University, Madrid University, Outstanding Lifetime Achievement Award from St. Joseph’s College, North Point; Honorary Doctorship and Professorship (Polish Academy of Science Pharmacological Society), Sansone Award, School of Medicine, Washington University, St. Louis, Missouri.

laboratory models of neurocritical care, arousal from coma, cardiac arrest, electrophysiology, neuropharmacology, orexin, global cerebral ischemia, neuroplasticity, neural monitoring devices, translational research, clinical trials

Weidong Le, MD, PhD, is a neurologist/neuroscientist with the major research interest in neurodegenerative disorders including Parkinson’s disease, Alzheimer’s disease and ALS. His research focus is cellular and molecular basis of neuronal injury in these neurodegenerative diseases. He was a Professor in Baylor College of Medicine and since 2013 he has been appointed as a Director of Center for Translational Research of Neurology Disease, and Vice President of 1st Affiliated Hospital, Dalian Medical University. He has published over 185 SCI papers in peer review journals and 7 scientific books.

Brain Imaging, Neuropsychiatry

Dr. Toborek has completed his MD and PhD from the Silesian Medical University, Poland, and completed his postdoctoral training at the University of Kentucky. He is the Vice-Chair for Research in the Department of Biochemistry and Molecular Biology. Research in Dr. Toborek’s laboratory has been focused on several aspects of vascular biology. Specific interest involves studies on the integrity of the blood-brain barrier (BBB) and how different pathological conditions can lead to the disruption and/or dysfunction of the BBB. He has published numerous manuscripts related to this field and has been serving as an editorial board member of many journals.

Dr. Toborek’s laboratory involve studies on the integrity of the blood-brain barrier (BBB) and how different pathological conditions can lead to the disruption and/or dysfunction of the BBB.

Dr. Othman Ghribi is an Associate professor at the Department of Pharmacology, Physiology and Therapeutics, University of North Dakota School of Medicine and Health Sciences, USA. He obtained his PHD degree in Neuropharmacology from Rene Descartes University, Paris, France in 1994. He published four book chapters, invited review papers and has more than 50 publications in different peer reviewed journals. Dr. Ghribi holds grants from the Centers of Biomedical Research Excellence and the National Institute of Environmental health Sciences/The National Institute of Health. Dr Ghribi obtained the Alzheimers and Related Diseases Research Award from the Virginia Center on Aging as well as the Dean David Wilson Academic Award in Neuroscience from the University of North Dakota.

Othman Ghribis Interests include role of the diet and environmental factors in Alzheimers and Parkinsons diseases, Tyrosine hydroxylase, alpha-synuclein, LXRs, Estrogen receptors, Oxysterols, Endoplasmic reticulum stress, Apoptosis, IGF-1, Leptin.

Dr. F.W. van Leeuwen, PhD is a neuroscientist with over 150 peer-reviewed scientific papers to his name. His team works at the University Maastricht. He was trained as a neurobiologist and obtained his PhD degree in 1980. After branching out into the field of molecular neurobiology in the nineties, he discovered a new mechanism, dubbed molecular misreading; the inaccurate conversion of genomic information into aberrant transcripts and mutant proteins (e.g. mutant ubiquitin B, UBB+1). These appeared to be present in the hallmarks (e.g. plaques and tangles) of sporadic Alzheimer and Down syndrome patients, but not in young non-demented controls. This was the cover story of Science 279, January 9th, 1998. The message is that the mutant proteins accumulate and contribute to neuronal dysfunctioning, e.g. by inhibiting the ubiquitin-proteasome system. This article has been named a “milestone paper”, and Dr. van Leeuwen has been invited to participate in an Alzheimer-100 book because it was 100 years ago that Dr. Alzheimer published his first article on the disease.

Neurodegenerative disorders,Down syndrome,Alzheimer’s disease

Professor Nazıroğlu has graduated from Veterinary Faculty, Fırat University (FU) at 1991 and he received his PhD (Physiology) in FU (1992-1996). Currently, he is working as Heads of Departments of Biophysics and Neurosciences in Suleyman Demirel University (SDU), Medical Faculty. As chair of congress, he organized 1st, 2nd, 3rd, 4th and 5th biennale International Congress in Cell Membrane and Oxidative Stress: Focus on Calcium Signaling and TRP channels since 2006, Isparta, Turkey. (www.cmos.org.tr). He is serving as an editorial member of several reputed journals like ‘Biological Trace Element Research’. He is also review editor in Frontiers in Membrane Physiology and Biophysics. He authored 188 international research and 11 review articles and 2852 citations in SCI-Thompson and 6 international book chapters. He has honored as NATO Research Fellowship, Martin-Luther University, Halle-Saale, Germany, (1999-2000), ‘Young Investigative Scientist Award (2001), UC-Berkeley, USA, Alexander von Humboldt (AvH) Research fellowship owner (2002-2005), Medical Faculty, RWTH-Aachen, Germany, Encouragement Award of Scientific and Tech. Res. Council (TUBITAK), Ankara, Turkey (2006), Howard Hudges Medical Institute (USA) support (2009) and Khwarizmi International Award (2012).

Epilepsy

Piotr Lewczuk heads the Laboratory for Clinical Neurochemistry and Neurochemical Dementia Diagnostics at the Department of Psychiatry and Psychotherapy Universitatsklinikum Erlangen. This lab is one of the mostly internationally recognized European leading centers for neurochemical diagnosis of dementia. The Laboratory is one of the five world-wide reference centers, together with the laboratories in Göteborg (S), Amsterdam (NL), Ghent (B), and Philadelphia (USA), in the Alzheimers Association supported project on CSF biomarkers international quality control. He is a member of the Steering Committee of this project. For more than ten years he has been working on diagnostic and research aspects of the CSF, including a large panel of neurologic and psychiatric disorders with a particular scope on neurodegenerating conditions, like Alzheimers disease.In 2004, he obtained the Certificate of Expertise from the German Society of Clinical Neurochemistry, to become one of seventy certified clinical neurochemists in Germany, and currently he is a member of the Extended Board of the German Society of Clinical Neurochemistry. Dr Lewczuk is also a member of the Scientific Advisory Board of the Alzheimer Diagnostic and Therapy Center at the Medical University of Wroclaw Poland in Scinawa and a consultant of a worldwide leading diagnostic biotech company Innogenetics Ghent Belgium.