Sha Mi
Biogen, USA
Biography
Sha Mi obtained her Ph.D. in Molecular and Cellular Biology from Rutgers University and her postdoctoral training in the laboratory of Dr. Richard Roberts (Nobel Laureate) at the Cold Spring Harbor Laboratory. Her major interests include the identification of novel CNS specific proteins involved in the regulation of neuronal cell survival, axonal regeneration, neuronal damage repair and remyelination. Her current focus is to identify therapeutics for the treatment of demyelination diseases such as MS. Her group is the first to identify proteins, LINGO-1 and DR6, that block remyelination repair in laboratory tissue culture and in animal disease models, and whose inhibition will allow for re-myelination and repair of damaged axons.
Abstract
Abstract : Blocking LINGO-1 for CNS Remyelination and Repair: From Discovery to Clinical Trials