Biomarkers for Early Neurodegeneration Detection
Biomarkers for Early Neurodegeneration Detection explore measurable biological indicators that reveal early stages of brain disorders before clinical symptoms appear. Biomarkers include molecular signatures in blood, cerebrospinal fluid, saliva, and imaging data such as amyloid accumulation, tau phosphorylation, neurofilament light chain, and synaptic dysfunction markers. Detecting these signals enables clinicians to forecast disease risk, classify disease subtypes, and monitor therapeutic response. Advances in proteomics, metabolomics, lipidomics, and genomics enhance the discovery of sensitive biomarkers that reflect cellular stress, inflammation, oxidative damage, and neurodegeneration. Digital biomarkers from gait patterns, voice analysis, sleep metrics, and cognitive behavior tracking offer non-invasive tools for real-world monitoring. Ultra-sensitive detection platforms such as single-molecule arrays further refine early diagnosis. By combining biological markers with AI-driven predictive models, clinicians gain powerful tools for personalized care, timely intervention, and improved outcomes in conditions like Alzheimer’s, Parkinson’s, ALS, and other neurodegenerative diseases.
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