Neuroinflammation Modulation & Immune Pathways

Neuroinflammation Modulation & Immune Pathways examines the complex interactions between the central nervous system and the immune system, highlighting their roles in both disease progression and healing. Persistent neuroinflammation is implicated in multiple neurological disorders, including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, epilepsy, and traumatic injuries. Understanding microglial activation, cytokine signaling, innate immune triggers, and inflammatory cascades provides insight into how immune dysregulation leads to neuronal damage. Research focuses on therapeutic strategies that modulate harmful inflammatory responses while preserving protective immune functions. Novel immunomodulatory agents, targeted cytokine inhibitors, and small molecule anti-inflammatory compounds are being explored to halt disease progression. Advances in mapping immune–brain communication also reveal how peripheral immunity influences neural health. Emerging approaches include nano-immunotherapy, gut–brain axis regulation, and cell-based immune engineering. By refining immune pathways, scientists aim to develop precise interventions that reduce neuroinflammation, support neural repair, and improve outcomes across diverse brain disorders.

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